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hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.

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Title: hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Authors: Chen Q; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Zhai Q; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Lin J; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Huang Y; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Li H; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Zhang C; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Yu Q; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Sun T; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China., Pan Y; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. aigui1993@126.com.
Source: The journal of headache and pain [J Headache Pain] 2026 Feb 07; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Zhai+Q%22">Zhai Q</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Yu+Q%22">Yu Q</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Sun+T%22">Sun T</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.<br /><searchLink fieldCode="AU" term="%22Pan+Y%22">Pan Y</searchLink>; Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. aigui1993@126.com.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2026 Feb 07; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10194-026-02288-0
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      – TitleFull: hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
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              M: 02
              Text: 2026 Feb 07
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