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A Comprehensive Review of Marketed KRAS Inhibitors and Degraders: Challenges and Opportunities.

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Title: A Comprehensive Review of Marketed KRAS Inhibitors and Degraders: Challenges and Opportunities.
Authors: Xu YX; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Bai YR; School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou, China., Li R; College of Biological Engineering, Henan University of Technology, Zhengzhou, China., Peng YM; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Liu TT; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Yang X; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Chen KT; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Jin ZP; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China., Liu HM; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Zhengzhou University, Zhengzhou, China., Yuan S; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.; School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou, China.; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Zhengzhou University, Zhengzhou, China.
Source: Medicinal research reviews [Med Res Rev] 2026 Jul; Vol. 46 (4), pp. 810-835. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8103150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1128 (Electronic) Linking ISSN: 01986325 NLM ISO Abbreviation: Med Res Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Comprehensive Review of Marketed KRAS Inhibitors and Degraders: Challenges and Opportunities.
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  Data: <searchLink fieldCode="AU" term="%22Xu+YX%22">Xu YX</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Bai+YR%22">Bai YR</searchLink>; School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; College of Biological Engineering, Henan University of Technology, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Peng+YM%22">Peng YM</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+TT%22">Liu TT</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+KT%22">Chen KT</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Jin+ZP%22">Jin ZP</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+HM%22">Liu HM</searchLink>; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Yuan+S%22">Yuan S</searchLink>; Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.; School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou, China.; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Zhengzhou University, Zhengzhou, China.
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  Data: <searchLink fieldCode="JN" term="%228103150%22">Medicinal research reviews</searchLink> [Med Res Rev] 2026 Jul; Vol. 46 (4), pp. 810-835. <i>Date of Electronic Publication: </i>2026 Feb 09.
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        Value: 10.1002/med.70035
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              Text: 2026 Jul
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              Y: 2026
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