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Berberine Alleviates Lipopolysaccharide-Induced Impairments in Neuroplasticity and Spatial Memory by Modulating Microglial Polarization via MAPK Signaling Inhibition.

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Title: Berberine Alleviates Lipopolysaccharide-Induced Impairments in Neuroplasticity and Spatial Memory by Modulating Microglial Polarization via MAPK Signaling Inhibition.
Authors: Jiang L; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Liao R; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Wang J; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Yang Y; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Sun J; Department of Medical Imaging Technology, Nanyang Medical College, Nanyang, 473004, Henan, China., Liu L; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Wang Y; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China, scu.edu.cn., Dong W; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn., Yu Y; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.
Source: Neural plasticity [Neural Plast] 2026 Feb 05; Vol. 2026, pp. 6795481. Date of Electronic Publication: 2026 Feb 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 100883417 Publication Model: eCollection Cited Medium: Internet ISSN: 1687-5443 (Electronic) Linking ISSN: 16875443 NLM ISO Abbreviation: Neural Plast Subsets: MEDLINE
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  Data: Berberine Alleviates Lipopolysaccharide-Induced Impairments in Neuroplasticity and Spatial Memory by Modulating Microglial Polarization via MAPK Signaling Inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liao+R%22">Liao R</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Medical Imaging Technology, Nanyang Medical College, Nanyang, 473004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China, scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Dong+W%22">Dong W</searchLink>; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Department of Histology and Embryology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.; Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China, swmu.edu.cn.
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              Text: 2026 Feb 05
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