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Effect of metformin dose reduction versus continuation at imeglimin initiation on glycemic control in type 2 diabetes: a retrospective real-world analysis.

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Title: Effect of metformin dose reduction versus continuation at imeglimin initiation on glycemic control in type 2 diabetes: a retrospective real-world analysis.
Authors: Fushimi Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan. fussy.k0113@med.kawasaki-m.ac.jp., Kimura T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Sanada J; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Ito T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Kubo M; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Dan K; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Okamoto Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Iwamoto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Iwamoto Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Shimoda M; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Nakanishi S; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Kaku K; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan., Kaneto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
Source: Acta diabetologica [Acta Diabetol] 2026 Apr; Vol. 63 (4), pp. 701-709. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9200299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5233 (Electronic) Linking ISSN: 09405429 NLM ISO Abbreviation: Acta Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of metformin dose reduction versus continuation at imeglimin initiation on glycemic control in type 2 diabetes: a retrospective real-world analysis.
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  Data: <searchLink fieldCode="AU" term="%22Fushimi+Y%22">Fushimi Y</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan. fussy.k0113@med.kawasaki-m.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kimura+T%22">Kimura T</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Sanada+J%22">Sanada J</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Kubo+M%22">Kubo M</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Dan+K%22">Dan K</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Okamoto+Y%22">Okamoto Y</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+H%22">Iwamoto H</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+Y%22">Iwamoto Y</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoda+M%22">Shimoda M</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Nakanishi+S%22">Nakanishi S</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Kaku+K%22">Kaku K</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneto+H%22">Kaneto H</searchLink>; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
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  Data: <searchLink fieldCode="JN" term="%229200299%22">Acta diabetologica</searchLink> [Acta Diabetol] 2026 Apr; Vol. 63 (4), pp. 701-709. <i>Date of Electronic Publication: </i>2026 Feb 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9200299 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-5233 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209405429%22">09405429 </searchLink><i>NLM ISO Abbreviation: </i>Acta Diabetol <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr
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