Modified EXTREME regimen versus modified TPEx regimen as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a multicenter, open-label, randomized, exploratory study (TEMPER study).
Saved in:
| Title: | Modified EXTREME regimen versus modified TPEx regimen as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a multicenter, open-label, randomized, exploratory study (TEMPER study). |
|---|---|
| Authors: | Suzuki M; Department of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Kishino A; Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Sugasawa M; Department of Head and Neck Surgery, International Medical Center, Saitama Medical University, Saitama, Japan., Fujii T; Department of Head and Neck Surgery, Osaka International Cancer Institute, Osaka Prefectural Hospital Organization, Osaka, Japan., Nakanome A; Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan., Terada T; Department of Otolaryngology-Head and Neck Surgery, Hyogo Medical University, Hyogo, Japan., Hirakawa H; Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan., Ueki Y; Department of Otolaryngology, Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Matsuo M; Department of Otorhinolaryngology Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ito R; Department of Otorhinolaryngology-Head and Neck Surgery, Osaka Rosai Hospital, Osaka, Japan., Hotomi M; Department of Otorhinolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan., Kanno M; Department of Otorhinolaryngology-Head and Neck Surgery, Medical Science, University of Fukui, Fukui, Japan., Watanabe A; Department of Otolaryngology-Head and Neck Surgery, Keiyukai Sapporo Hospital, Sapporo, Japan., Kitamura Y; Department of Otorhinolaryngology-Head and Neck Surgery, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan., Okami K; Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Tokai University, Kanagawa, Japan., Endo K; Division of Otolaryngology-Head and Neck Surgery, School of Medicine, Kanazawa University, Ishikawa, Japan., Ono T; Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Fukuoka, Japan., Hirano S; Department of Otolaryngology Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Omura G; Department of Head and Neck Surgery, National Cancer Center Hospital, Tokyo, Japan., Omori K; Department of Head and Neck Oncology and Innovative Treatment, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Yamamoto Y; Osaka General Medical Center Department of Otorhinolaryngology-Head and Neck Surgery, Osaka, Japan., Shimokawa M; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Ube, Japan., Inohara H; Department of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. hinohara@ent.med.osaka-u.ac.jp. |
| Source: | International journal of clinical oncology [Int J Clin Oncol] 2026 Apr; Vol. 31 (4), pp. 611-620. Date of Electronic Publication: 2026 Feb 09. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41661417 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Modified EXTREME regimen versus modified TPEx regimen as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a multicenter, open-label, randomized, exploratory study (TEMPER study). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Suzuki+M%22">Suzuki M</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Kishino+A%22">Kishino A</searchLink>; Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Sugasawa+M%22">Sugasawa M</searchLink>; Department of Head and Neck Surgery, International Medical Center, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Fujii+T%22">Fujii T</searchLink>; Department of Head and Neck Surgery, Osaka International Cancer Institute, Osaka Prefectural Hospital Organization, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakanome+A%22">Nakanome A</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Terada+T%22">Terada T</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Hyogo Medical University, Hyogo, Japan.<br /><searchLink fieldCode="AU" term="%22Hirakawa+H%22">Hirakawa H</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ueki+Y%22">Ueki Y</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuo+M%22">Matsuo M</searchLink>; Department of Otorhinolaryngology Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+R%22">Ito R</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Osaka Rosai Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hotomi+M%22">Hotomi M</searchLink>; Department of Otorhinolaryngology Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kanno+M%22">Kanno M</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Medical Science, University of Fukui, Fukui, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+A%22">Watanabe A</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Keiyukai Sapporo Hospital, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamura+Y%22">Kitamura Y</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Okami+K%22">Okami K</searchLink>; Department of Otolaryngology, Head and Neck Surgery, School of Medicine, Tokai University, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Endo+K%22">Endo K</searchLink>; Division of Otolaryngology-Head and Neck Surgery, School of Medicine, Kanazawa University, Ishikawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ono+T%22">Ono T</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Hirano+S%22">Hirano S</searchLink>; Department of Otolaryngology Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Omura+G%22">Omura G</searchLink>; Department of Head and Neck Surgery, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Omori+K%22">Omori K</searchLink>; Department of Head and Neck Oncology and Innovative Treatment, Graduate School of Medicine, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+Y%22">Yamamoto Y</searchLink>; Osaka General Medical Center Department of Otorhinolaryngology-Head and Neck Surgery, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shimokawa+M%22">Shimokawa M</searchLink>; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Ube, Japan.<br /><searchLink fieldCode="AU" term="%22Inohara+H%22">Inohara H</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, The University of Osaka, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. hinohara@ent.med.osaka-u.ac.jp. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229616295%22">International journal of clinical oncology</searchLink> [Int J Clin Oncol] 2026 Apr; Vol. 31 (4), pp. 611-620. <i>Date of Electronic Publication: </i>2026 Feb 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Tokyo%22">Springer-Verlag Tokyo </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>9616295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1437-7772 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213419625%22">13419625 </searchLink><i>NLM ISO Abbreviation: </i>Int J Clin Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41661417 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10147-026-02964-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 611 Titles: – TitleFull: Modified EXTREME regimen versus modified TPEx regimen as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma: a multicenter, open-label, randomized, exploratory study (TEMPER study). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Suzuki M – PersonEntity: Name: NameFull: Kishino A – PersonEntity: Name: NameFull: Sugasawa M – PersonEntity: Name: NameFull: Fujii T – PersonEntity: Name: NameFull: Nakanome A – PersonEntity: Name: NameFull: Terada T – PersonEntity: Name: NameFull: Hirakawa H – PersonEntity: Name: NameFull: Ueki Y – PersonEntity: Name: NameFull: Matsuo M – PersonEntity: Name: NameFull: Ito R – PersonEntity: Name: NameFull: Hotomi M – PersonEntity: Name: NameFull: Kanno M – PersonEntity: Name: NameFull: Watanabe A – PersonEntity: Name: NameFull: Kitamura Y – PersonEntity: Name: NameFull: Okami K – PersonEntity: Name: NameFull: Endo K – PersonEntity: Name: NameFull: Ono T – PersonEntity: Name: NameFull: Hirano S – PersonEntity: Name: NameFull: Omura G – PersonEntity: Name: NameFull: Omori K – PersonEntity: Name: NameFull: Yamamoto Y – PersonEntity: Name: NameFull: Shimokawa M – PersonEntity: Name: NameFull: Inohara H IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1437-7772 Numbering: – Type: volume Value: 31 – Type: issue Value: 4 Titles: – TitleFull: International journal of clinical oncology Type: main |
| ResultId | 1 |
