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Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold.

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Title: Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold.
Authors: Horie H; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Fukumitsu K; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. tsurugi@kuhp.kyoto-u.ac.jp.; Department of Surgery, Kyoto Katsura Hospital, 17 Yamadahirao-cho, Nisigyo-ku, Kyoto, 615-8256, Japan. tsurugi@kuhp.kyoto-u.ac.jp., Hanabata Y; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Karasuyama T; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Iwaki K; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Munekage F; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Makino K; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Ito T; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Tomofuji K; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Kojima H; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Ogiso S; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Uebayashi EY; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Uematsu H; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan., Coppo R; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan., Onuma K; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan., Inoue M; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan., Ishii T; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan., Hatano E; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Source: Scientific reports [Sci Rep] 2026 Feb 10; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Horie+H%22">Horie H</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Fukumitsu+K%22">Fukumitsu K</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. tsurugi@kuhp.kyoto-u.ac.jp.; Department of Surgery, Kyoto Katsura Hospital, 17 Yamadahirao-cho, Nisigyo-ku, Kyoto, 615-8256, Japan. tsurugi@kuhp.kyoto-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Hanabata+Y%22">Hanabata Y</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Karasuyama+T%22">Karasuyama T</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Iwaki+K%22">Iwaki K</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Munekage+F%22">Munekage F</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Makino+K%22">Makino K</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Tomofuji+K%22">Tomofuji K</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Kojima+H%22">Kojima H</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Ogiso+S%22">Ogiso S</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Uebayashi+EY%22">Uebayashi EY</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Uematsu+H%22">Uematsu H</searchLink>; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan.<br /><searchLink fieldCode="AU" term="%22Coppo+R%22">Coppo R</searchLink>; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan.<br /><searchLink fieldCode="AU" term="%22Onuma+K%22">Onuma K</searchLink>; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+M%22">Inoue M</searchLink>; Department of Clinical Bio-Resource Research and Development, Graduate School of Medicine, Kyoto University, 46-29 Yosida-shimo-adachi-cho, Sakyo-ku, Kyoto, 606- 8501, Japan.<br /><searchLink fieldCode="AU" term="%22Ishii+T%22">Ishii T</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Hatano+E%22">Hatano E</searchLink>; Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogo-in Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
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