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Clinical outcomes of genomically guided trametinib monotherapy across cancer types: results from the IMPRESS-Norway trial.

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Title: Clinical outcomes of genomically guided trametinib monotherapy across cancer types: results from the IMPRESS-Norway trial.
Authors: Slørdahl KS; Department of Oncology, Oslo University Hospital, Oslo, Norway. katslo@ous-hf.no., Puco K; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Falk RS; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway., Dyvik I; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway]., Brabrand S; Department of Oncology, Oslo University Hospital, Oslo, Norway., Niehusmann P; Department of Oncology, Oslo University Hospital, Oslo, Norway; Department of Pathology, Oslo University Hospital, Oslo, Norway]., Steinskog ESS; Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway., Blix ES; Department of Oncology, University Hospital of North Norway, Tromsø, Norway., Flobak Å; The Cancer Clinic, St. Olavs University hospital, Trondheim, Norway; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Department of Biotechnology and Nanomedicine, Sintef Industry, Trondheim, Norway., Oppedal IA; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway., Meltzer S; Department of Oncology, Akershus University Hospital, Lørenskog, Norway., Torkildsen CF; Department of Gynecology and Obstetrics, Stavanger University Hospital, Stavanger, Norway; Centre for cancer biomarkers, CCBIO, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Heidelberg University Hospital, Heidelberg, Germany., Blakstad H; Department of Oncology, Oslo University Hospital, Oslo, Norway., Lindemann K; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; Section for gynecological oncology, Department of Surgical Oncology, Oslo University., Smeland S; Department of Oncology, Oslo University Hospital, Oslo, Norway., Amundsen A; Department of Oncology, University Hospital of North Norway, Tromsø, Norway., Taskén K; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Helland Å; Department of Oncology, Oslo University Hospital, Oslo, Norway; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Corporate Authors: InPred Consortium
Source: Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2026 Feb 10; Vol. 65, pp. 90-96. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Medical Journals Sweden AB Country of Publication: Sweden NLM ID: 8709065 Publication Model: Electronic Cited Medium: Internet ISSN: 1651-226X (Electronic) Linking ISSN: 0284186X NLM ISO Abbreviation: Acta Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical outcomes of genomically guided trametinib monotherapy across cancer types: results from the IMPRESS-Norway trial.
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  Data: <searchLink fieldCode="AU" term="%22Slørdahl+KS%22">Slørdahl KS</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway. katslo@ous-hf.no.<br /><searchLink fieldCode="AU" term="%22Puco+K%22">Puco K</searchLink>; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Falk+RS%22">Falk RS</searchLink>; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dyvik+I%22">Dyvik I</searchLink>; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway].<br /><searchLink fieldCode="AU" term="%22Brabrand+S%22">Brabrand S</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Niehusmann+P%22">Niehusmann P</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway; Department of Pathology, Oslo University Hospital, Oslo, Norway].<br /><searchLink fieldCode="AU" term="%22Steinskog+ESS%22">Steinskog ESS</searchLink>; Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Blix+ES%22">Blix ES</searchLink>; Department of Oncology, University Hospital of North Norway, Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Flobak+Å%22">Flobak Å</searchLink>; The Cancer Clinic, St. Olavs University hospital, Trondheim, Norway; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Department of Biotechnology and Nanomedicine, Sintef Industry, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Oppedal+IA%22">Oppedal IA</searchLink>; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Meltzer+S%22">Meltzer S</searchLink>; Department of Oncology, Akershus University Hospital, Lørenskog, Norway.<br /><searchLink fieldCode="AU" term="%22Torkildsen+CF%22">Torkildsen CF</searchLink>; Department of Gynecology and Obstetrics, Stavanger University Hospital, Stavanger, Norway; Centre for cancer biomarkers, CCBIO, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Blakstad+H%22">Blakstad H</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Lindemann+K%22">Lindemann K</searchLink>; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; Section for gynecological oncology, Department of Surgical Oncology, Oslo University.<br /><searchLink fieldCode="AU" term="%22Smeland+S%22">Smeland S</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Amundsen+A%22">Amundsen A</searchLink>; Department of Oncology, University Hospital of North Norway, Tromsø, Norway.<br /><searchLink fieldCode="AU" term="%22Taskén+K%22">Taskén K</searchLink>; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Helland+Å%22">Helland Å</searchLink>; Department of Oncology, Oslo University Hospital, Oslo, Norway; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
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  Data: <searchLink fieldCode="JN" term="%228709065%22">Acta oncologica (Stockholm, Sweden)</searchLink> [Acta Oncol] 2026 Feb 10; Vol. 65, pp. 90-96. <i>Date of Electronic Publication: </i>2026 Feb 10.
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