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A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator.

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Title: A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator.
Authors: Herraiz A; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain., Rodríguez-San-Pedro A; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain.; Universidad Autónoma de Madrid, Escuela de Doctorado Cantoblanco, Madrid, Spain., Casquero-Veiga M; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain.; Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD), Madrid, Spain., Cossío U; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain., Arias-Ramos N; Institute for Biomedical Research Sols-Morreale (IIBM), CSIC-UAM, Madrid, Spain.; Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain., Gutiérrez L; Instituto de Nanociencia y Materiales de Aragón, INMA (CSIC-Universidad de Zaragoza) and CIBER-BBN, Zaragoza, Spain., Romero-Sanz E; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain., Luján-Rodríguez VM; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain., Cerón C; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain., Oteo M; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain., González-Paredes A; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain., López-Larrubia P; Institute for Biomedical Research Sols-Morreale (IIBM), CSIC-UAM, Madrid, Spain.; Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain., Rosales RTM; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK., Cortes-Canteli M; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain.; Centro de Neurociencias Cajal - CSIC, Alcalá de Henares, Spain., Morcillo MA; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain., Ruiz-Cabello J; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.; NMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, University Complutense Madrid, Madrid, Spain., Pellico J; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.; Institute of Materials Science of Barcelona (ICMAB-CSIC), Campus of the UAB, Bellaterra, Spain., Herranz F; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain. fherranz@iqm.csic.es.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain. fherranz@iqm.csic.es.
Source: Npj imaging [Npj Imaging] 2026 Feb 10; Vol. 4 (1), pp. 8. Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: Switzerland NLM ID: 9918733285306676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-197X (Electronic) Linking ISSN: 2948197X NLM ISO Abbreviation: Npj Imaging Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator.
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  Data: <searchLink fieldCode="AU" term="%22Herraiz+A%22">Herraiz A</searchLink>; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-San-Pedro+A%22">Rodríguez-San-Pedro A</searchLink>; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain.; Universidad Autónoma de Madrid, Escuela de Doctorado Cantoblanco, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Casquero-Veiga+M%22">Casquero-Veiga M</searchLink>; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain.; Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cossío+U%22">Cossío U</searchLink>; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain.<br /><searchLink fieldCode="AU" term="%22Arias-Ramos+N%22">Arias-Ramos N</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), CSIC-UAM, Madrid, Spain.; Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gutiérrez+L%22">Gutiérrez L</searchLink>; Instituto de Nanociencia y Materiales de Aragón, INMA (CSIC-Universidad de Zaragoza) and CIBER-BBN, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Romero-Sanz+E%22">Romero-Sanz E</searchLink>; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Luján-Rodríguez+VM%22">Luján-Rodríguez VM</searchLink>; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cerón+C%22">Cerón C</searchLink>; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Oteo+M%22">Oteo M</searchLink>; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22González-Paredes+A%22">González-Paredes A</searchLink>; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Larrubia+P%22">López-Larrubia P</searchLink>; Institute for Biomedical Research Sols-Morreale (IIBM), CSIC-UAM, Madrid, Spain.; Biomedical Research Networking Centre on Rare Diseases (CIBERER), Institute of Health Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rosales+RTM%22">Rosales RTM</searchLink>; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cortes-Canteli+M%22">Cortes-Canteli M</searchLink>; Cardiovascular Risk Factors and Brain Function Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain.; Centro de Neurociencias Cajal - CSIC, Alcalá de Henares, Spain.<br /><searchLink fieldCode="AU" term="%22Morcillo+MA%22">Morcillo MA</searchLink>; Unidad de Aplicaciones Médicas de las Radiaciones Ionizantes, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz-Cabello+J%22">Ruiz-Cabello J</searchLink>; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Donostia San Sebastián, Spain.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.; NMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, University Complutense Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Pellico+J%22">Pellico J</searchLink>; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.; Institute of Materials Science of Barcelona (ICMAB-CSIC), Campus of the UAB, Bellaterra, Spain.<br /><searchLink fieldCode="AU" term="%22Herranz+F%22">Herranz F</searchLink>; Nanomedicina, Imagen y modelos 3D (NI3D), Instituto de Química Médica (IQM/CSIC), Madrid, Spain. fherranz@iqm.csic.es.; CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain. fherranz@iqm.csic.es.
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