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Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study.

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Title: Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study.
Authors: Kuang S; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands. sheng.kuang@maastrichtuniversity.nl., Schuitmaker L; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Wu M; Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Salahuddin Z; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., van der Wiel A; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., van de Laak J; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Lieuwes N; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Biemans R; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Jung J; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Yaromina A; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Dubois LJ; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Woodruff HC; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands., Lambin P; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.; Department of Radiology and Nuclear Medicine, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center + , Maastricht, Netherlands.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Feb 10; Vol. 10 (1). Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
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  Data: Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study.
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  Data: <searchLink fieldCode="AU" term="%22Kuang+S%22">Kuang S</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands. sheng.kuang@maastrichtuniversity.nl.<br /><searchLink fieldCode="AU" term="%22Schuitmaker+L%22">Schuitmaker L</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Salahuddin+Z%22">Salahuddin Z</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Wiel+A%22">van der Wiel A</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+de+Laak+J%22">van de Laak J</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Lieuwes+N%22">Lieuwes N</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Biemans+R%22">Biemans R</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Jung+J%22">Jung J</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Yaromina+A%22">Yaromina A</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Dubois+LJ%22">Dubois LJ</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Woodruff+HC%22">Woodruff HC</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Lambin+P%22">Lambin P</searchLink>; Department of Precision Medicine, GROW - Research Institute for Oncology and Reproduction, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.; Department of Radiology and Nuclear Medicine, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center + , Maastricht, Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Feb 10; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Feb 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 10
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