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A literature review of macular holes in age-related macular degeneration: insights into the pathogenesis, prognosis and surgical outcomes.

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Title: A literature review of macular holes in age-related macular degeneration: insights into the pathogenesis, prognosis and surgical outcomes.
Authors: Christou EE; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK. evitachristou@gmail.com.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. evitachristou@gmail.com., Ivanova T; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Patton N; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Moussa G; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Kiraly P; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences & NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Huelin FJ; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.; Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain., MacLaren RE; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences & NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Jalil A; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Source: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2026 Jun; Vol. 264 (6), pp. 1649-1659. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8205248 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-702X (Electronic) Linking ISSN: 0721832X NLM ISO Abbreviation: Graefes Arch Clin Exp Ophthalmol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Christou+EE%22">Christou EE</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK. evitachristou@gmail.com.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. evitachristou@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ivanova+T%22">Ivanova T</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Patton+N%22">Patton N</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Moussa+G%22">Moussa G</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Kiraly+P%22">Kiraly P</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences & NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Huelin+FJ%22">Huelin FJ</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.; Department of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22MacLaren+RE%22">MacLaren RE</searchLink>; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences & NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jalil+A%22">Jalil A</searchLink>; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8205248 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1435-702X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220721832X%22">0721832X </searchLink><i>NLM ISO Abbreviation: </i>Graefes Arch Clin Exp Ophthalmol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00417-026-07146-y
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      – Code: eng
        Text: English
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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            – TitleFull: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
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