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Ancestry-Associated Performance Variability of Open-Source AI Models for EGFR Prediction in Lung Cancer.

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Title: Ancestry-Associated Performance Variability of Open-Source AI Models for EGFR Prediction in Lung Cancer.
Authors: Rakaee M; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway., Nassar AH; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Medical Oncology, Yale Cancer Center, Yale New Haven Hospital, New Haven, Connecticut., Tafavvoghi M; Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway.; Department of Clinical Pathology, University Hospital of North Norway, Tromso, Norway., Jabar F; Department of Surgery and Cancer, Imperial College London, London, United Kingdom.; Department of Clinical Pathology, University Hospital of North Norway, Tromso, Norway., Bou Farhat E; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Adib E; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Andersen S; Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway., Busund LR; Department of Clinical Pathology, University Hospital of North Norway, Tromso, Norway., Pøhl M; Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Helland Å; Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway., Gusev A; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Ricciuti B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Donnem T; Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway., Kwiatkowski DJ; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Source: JAMA oncology [JAMA Oncol] 2026 Apr 01; Vol. 12 (4), pp. 402-406.
Publication Type: Journal Article
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101652861 Publication Model: Print Cited Medium: Internet ISSN: 2374-2445 (Electronic) Linking ISSN: 23742437 NLM ISO Abbreviation: JAMA Oncol Subsets: MEDLINE
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