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Exploration and discovery of treatment targets for primary biliary cholangitis based on plasma and cerebrospinal fluid proteomics: A multicenter mendelian randomization study.

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Title: Exploration and discovery of treatment targets for primary biliary cholangitis based on plasma and cerebrospinal fluid proteomics: A multicenter mendelian randomization study.
Authors: Xi J; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China., Wang S; Department of Neurology, The First Hospital of Jilin University, ChangChun, Jilin, China.; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Chen J; Department of Radiology, The First Hospital of Jilin University, Chang Chun, Jilin, China., Law JCS; Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China., Wang J; First Operating Room, The First Hospital of Jilin University, Changchun, Jilin, China., Lee GH; Division of Gastroenterology and Hepatology, Department of Surgery, National University Hospital Singapore, Singapore., Fan Z; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China., Lv G; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China., Chen Y; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China.
Source: PloS one [PLoS One] 2026 Feb 12; Vol. 21 (2), pp. e0340166. Date of Electronic Publication: 2026 Feb 12 (Print Publication: 2026).
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploration and discovery of treatment targets for primary biliary cholangitis based on plasma and cerebrospinal fluid proteomics: A multicenter mendelian randomization study.
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  Data: <searchLink fieldCode="AU" term="%22Xi+J%22">Xi J</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Neurology, The First Hospital of Jilin University, ChangChun, Jilin, China.; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Radiology, The First Hospital of Jilin University, Chang Chun, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Law+JCS%22">Law JCS</searchLink>; Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; First Operating Room, The First Hospital of Jilin University, Changchun, Jilin, China.<br /><searchLink fieldCode="AU" term="%22Lee+GH%22">Lee GH</searchLink>; Division of Gastroenterology and Hepatology, Department of Surgery, National University Hospital Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Fan+Z%22">Fan Z</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Lv+G%22">Lv G</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China.; China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Feb 12; Vol. 21 (2), pp. e0340166. <i>Date of Electronic Publication: </i>2026 Feb 12 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41678453
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              Text: 2026 Feb 12
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