Association of high-risk CT coronary artery plaque features with major adverse cardiovascular events: a prespecified secondary analysis of the DISCHARGE trial.
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| Title: | Association of high-risk CT coronary artery plaque features with major adverse cardiovascular events: a prespecified secondary analysis of the DISCHARGE trial. |
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| Authors: | Szilveszter B; Heart and Vascular Center, Semmelweis University, Budapest, Hungary. szilveszter.balint@semmelweis.hu., Biavati F; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Sørum C; Department of Cardiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiksberg, Denmark., Benedek T; Department of Internal Medicine, Clinic of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania.; County Clinical Emergency Hospital Targu Mures, Targu Mures, Romania., Donnelly P; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom., Rodriguez-Palomares JF; Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigacion Biomedica en Red, Madrid, Spain., Erglis A; Department of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia.; University of Latvia, Riga, Latvia., Štěchovský C; Department of Cardiology, Motol University Hospital, Prague, Czech Republic., Šakalytė G; Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.; Department of Cardiology, Hospital of Lithuanian University of Health Sciences, Kaunas, Lithuania., Ađić NČ; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.; Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia., Gutberlet M; Department of Radiology, University of Leipzig Heart Centre, Leipzig, Germany., Dodd JD; Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland.; School of Medicine, University College Dublin, Dublin, Ireland., Diez I; Department of Cardiology, Basurto Hospital, Bilbao, Spain., Davis G; Department of Cardiology, Aintree University Hospital, Liverpool, United Kingdom.; Edge Hill University, Ormskirk, United Kingdom., Zimmermann E; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Kepka C; National Institute of Cardiology, Warsaw, Poland., Vidakovic R; Department of Cardiology, Internal Medicine Clinic, Clinical Hospital Center Zemun, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Francone M; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.; Department of Biomedical Sciences, Humanitas University and IRCCS Humanitas Research Hospital, Milan, Italy., Ilnicka-Suckiel M; Department of Cardiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland., Plank F; Department of Internal Medicine III, Department of Cardiology, Innsbruck Medical University, Innsbruck, Austria., Knuuti J; Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland., Faria R; Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia-Espinho, Vila Nova de Gaia, Portugal., Schröder S; Department of Cardiology, Alb Fils Kliniken, Göppingen, Germany., Berry C; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom.; Golden Jubilee National Hospital, Clydebank, United Kingdom., Saba L; Department of Radiology, University of Cagliari, Cagliari, Italy., Ruzsics B; Department of Cardiology, Liverpool University Hospital NHS FT, Liverpool, United Kingdom.; Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom., Rieckmann N; Institute of Public Health, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Kubiak C; ECRIN-ERIC (European Clinical Research Infrastructure Network-European Research Infrastructure Consortium), Paris, France., Hansen KS; Department of Public Health, Section for Health Services Research, University of Copenhagen, Copenhagen, Denmark., Müller-Nordhorn J; Bavarian Cancer Registry, Bavarian Health and Food Safety Authority, Munich, Germany., Maurovich-Horvat P; Heart and Vascular Center, Semmelweis University, Budapest, Hungary.; Department of Radiology, Medical Imaging Center, Semmelweis University, Budapest, Hungary., Vall-Lamora HD; Department of Biomedicine, University of Copenhagen, Copenhagen, Denmark., Benedek I; Center of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, Targu Mures, Romania., Orr C; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom., Valente F; Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigacion Biomedica en Red, Madrid, Spain.; Department of Radiology, Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain., Zvaigzne L; Department of Radiology, Paul Stradins Clinical University Hospital, Riga, Latvia., Suchánek V; Department of Imaging Methods, Motol University Hospital, Prague, Czech Republic., Jankauskas A; Institute of Cardiology, Lithuanian University of Health Sciences, Department of Radiology, Kaunas Clinics, Kaunas, Lithuania., Ađić F; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.; Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia., Woinke M; Department of Cardiology, University of Leipzig Heart Centre, Leipzig, Germany., Mulvihill N; Department of Cardiology, St. Vincent's University Hospital, Dublin, Ireland., Lecumberri I; Department of Radiology, Basurto Hospital, Bilbao, Spain., Thwaite E; Department of Radiology, Aintree University Hospital, Liverpool, United Kingdom., Kruk M; National Institute of Cardiology, Warsaw, Poland., Neskovic AN; Department of Cardiology, Internal Medicine Clinic, Clinical Hospital Center Zemun, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Mancone M; Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Kuśmierz D; Department of Radiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland., Feuchtner GM; Department of Radiology, Innsbruck Medical University, Innsbruck, Austria., Pietilä M; Heart Center, Turku University Hospital and University of Turku, Turku, Finland.; Administrative Centre, Health Care District of Southwestern Finland, Turku, Finland., Ribeiro VG; Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia-Espinho, Vila Nova de Gaia, Portugal., Drosch T; Department of Cardiology, Alb Fils Kliniken, Göppingen, Germany., Delles C; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom., Boi A; Department of Cardiology, Azienda Ospedaliera Brotzu, Cagliari, Italy., Fisher M; Department of Cardiology, Liverpool University Hospital NHS FT, Liverpool, United Kingdom.; Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, United Kingdom., Merkely B; Heart and Vascular Center, Semmelweis University, Budapest, Hungary., Hansen TF; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark., Aurelian R; Department of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Tirgu Mures, Romania., Kelly S; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom., Del Blanco BG; Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigacion Biomedica en Red, Madrid, Spain.; Department of Radiology, Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain., Rubio A; Department of Cardiology, Basurto Hospital, Bilbao, Spain., Boussoussou M; Heart and Vascular Center, Semmelweis University, Budapest, Hungary., Jørgensen T; Department of Cardiology, Amager-Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark., Rodean I; Center of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, Targu Mures, Romania., Regan S; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom., Calabria HC; Department of Radiology, Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain., Vattay B; Heart and Vascular Center, Semmelweis University, Budapest, Hungary., Hodas R; Department of Internal Medicine, Clinic of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania., Napp AE; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Haase R; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Feger S; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Mohamed MMA; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Serna-Higuita LM; Department of Clinical Epidemiology and Applied Biostatistics, Universitätsklinikum Tübingen, Tübingen, Germany., Neumann K; Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Dreger H; Department of Cardiology and Angiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Rief M; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Wieske V; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Williams MC; British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland., Estrella M; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Bosserdt M; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Martus P; Department of Clinical Epidemiology and Applied Biostatistics, Universitätsklinikum Tübingen, Tübingen, Germany., Kofoed KF; Department of Cardiology, Copenhagen University Hospital - Rigshospitalet & Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Radiology, Copenhagen University Hospital - Rigshospitalet & Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dewey M; Department of Radiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany.; Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Charité Mitte, Berlin, Germany.; Berlin University Alliance, Berlin, Germany. |
| Source: | European radiology [Eur Radiol] 2026 Jul; Vol. 36 (7), pp. 5502-5517. Date of Electronic Publication: 2026 Feb 13. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Pragmatic Clinical Trial |
| Journal Info: | Publisher: Springer International Country of Publication: Germany NLM ID: 9114774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1084 (Electronic) Linking ISSN: 09387994 NLM ISO Abbreviation: Eur Radiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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