Inhibition of cytomegalovirus reactivation by ex vivo treatment of human kidneys with the SYN002 immunotoxin.

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Title: Inhibition of cytomegalovirus reactivation by ex vivo treatment of human kidneys with the SYN002 immunotoxin.
Authors: Poole E; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Electronic address: elp27@cam.ac.uk., Hosgood SA; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Appiah E; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Elder E; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Moulding S; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Carlsson F; Synklino A/S, Frederiksborggade, Copenhagen, Denmark., Drzazga AK; Department of Biomedical Sciences, University of Copenhagen, Laboratory for Molecular Pharmacology, Copenhagen, Denmark., Rosenkilde MM; Department of Biomedical Sciences, University of Copenhagen, Laboratory for Molecular Pharmacology, Copenhagen, Denmark., Lantto J; Synklino A/S, Frederiksborggade, Copenhagen, Denmark., McGowan I; Synklino A/S, Frederiksborggade, Copenhagen, Denmark., Kledal T; Synklino A/S, Frederiksborggade, Copenhagen, Denmark., Nicholson ML; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Sinclair J; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
Source: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2026 Jun; Vol. 26 (6), pp. 1339-1348. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE
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  Data: Inhibition of cytomegalovirus reactivation by ex vivo treatment of human kidneys with the SYN002 immunotoxin.
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  Data: <searchLink fieldCode="AU" term="%22Poole+E%22">Poole E</searchLink>; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. Electronic address: elp27@cam.ac.uk.<br /><searchLink fieldCode="AU" term="%22Hosgood+SA%22">Hosgood SA</searchLink>; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Appiah+E%22">Appiah E</searchLink>; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Elder+E%22">Elder E</searchLink>; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Moulding+S%22">Moulding S</searchLink>; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Carlsson+F%22">Carlsson F</searchLink>; Synklino A/S, Frederiksborggade, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Drzazga+AK%22">Drzazga AK</searchLink>; Department of Biomedical Sciences, University of Copenhagen, Laboratory for Molecular Pharmacology, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rosenkilde+MM%22">Rosenkilde MM</searchLink>; Department of Biomedical Sciences, University of Copenhagen, Laboratory for Molecular Pharmacology, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lantto+J%22">Lantto J</searchLink>; Synklino A/S, Frederiksborggade, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22McGowan+I%22">McGowan I</searchLink>; Synklino A/S, Frederiksborggade, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kledal+T%22">Kledal T</searchLink>; Synklino A/S, Frederiksborggade, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Nicholson+ML%22">Nicholson ML</searchLink>; Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sinclair+J%22">Sinclair J</searchLink>; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
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  Data: <searchLink fieldCode="JN" term="%22100968638%22">American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons</searchLink> [Am J Transplant] 2026 Jun; Vol. 26 (6), pp. 1339-1348. <i>Date of Electronic Publication: </i>2026 Feb 13.
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