Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment.

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Title: Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment.
Authors: Furutani Y; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan., Oshima H; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan., Hong CP; YiPSCELL Inc., Seoul, Republic of Korea., Choi S; YiPSCELL Inc., Seoul, Republic of Korea., Machi R; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan., Nakayama M; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan., Murakami K; Division of Epithelial Stem Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan., Yagi S; Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kanazawa University, Kanazawa, Japan., Ito Y; Department of Molecular and Cellular Pathology, Kanazawa University, Kanazawa, Japan., Maeda D; Department of Molecular and Cellular Pathology, Kanazawa University, Kanazawa, Japan., Inaki N; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan., Barker N; Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, NUS, Singapore, Singapore., Oshima M; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan. oshimam@staff.kanazawa-u.ac.jp.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan. oshimam@staff.kanazawa-u.ac.jp.
Source: Nature communications [Nat Commun] 2026 Feb 14; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment.
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  Data: <searchLink fieldCode="AU" term="%22Furutani+Y%22">Furutani Y</searchLink>; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Oshima+H%22">Oshima H</searchLink>; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hong+CP%22">Hong CP</searchLink>; YiPSCELL Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; YiPSCELL Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Machi+R%22">Machi R</searchLink>; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Nakayama+M%22">Nakayama M</searchLink>; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+K%22">Murakami K</searchLink>; Division of Epithelial Stem Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Yagi+S%22">Yagi S</searchLink>; Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+Y%22">Ito Y</searchLink>; Department of Molecular and Cellular Pathology, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Maeda+D%22">Maeda D</searchLink>; Department of Molecular and Cellular Pathology, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Inaki+N%22">Inaki N</searchLink>; Department of Gastrointestinal Surgery, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Barker+N%22">Barker N</searchLink>; Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, NUS, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Oshima+M%22">Oshima M</searchLink>; Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan. oshimam@staff.kanazawa-u.ac.jp.; WPI Nano Life Science Institute (NanoLSI), Kanazawa University, Kanazawa, Japan. oshimam@staff.kanazawa-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 14; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 14.
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              Text: 2026 Feb 14
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