Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model.
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| Title: | Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model. |
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| Authors: | Penny LK; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK.; TauRx Therapeutics Management Ltd., Aberdeen, UK., Arastoo M; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK. mohammad.arastoo@abdn.ac.uk.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK. mohammad.arastoo@abdn.ac.uk., Lofthouse R; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK., Abdallah A; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK., Imoesi PI; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Schwab K; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Shiells H; TauRx Therapeutics Management Ltd., Aberdeen, UK., Melis V; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Riedel G; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Harrington CR; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; GT Diagnostics (UK) Ltd., Aberdeen, UK.; TauRx Therapeutics Management Ltd., Aberdeen, UK., Wischik CM; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; GT Diagnostics (UK) Ltd., Aberdeen, UK.; TauRx Therapeutics Management Ltd., Aberdeen, UK., Porter A; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK., Palliyil S; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK. |
| Source: | Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Feb 14; Vol. 18 (1). Date of Electronic Publication: 2026 Feb 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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