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Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform.

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Title: Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform.
Authors: Strickland MR; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University in Saint Louis, MO, USA., Wang Z; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Golden LR; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA., Wang H; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Lu P; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA., Ren Y; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Tabor GT; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA., Zhao N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Ulrich JD; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in Saint Louis, St. Louis, MO, USA., Han X; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Peng J; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Holtzman DM; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in Saint Louis, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in Saint Louis, St. Louis, MO, USA. Electronic address: holtzman@wustl.edu.
Source: Journal of lipid research [J Lipid Res] 2026 Mar; Vol. 67 (3), pp. 101000. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform.
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  Data: <searchLink fieldCode="AU" term="%22Strickland+MR%22">Strickland MR</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University in Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Golden+LR%22">Golden LR</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lu+P%22">Lu P</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Tabor+GT%22">Tabor GT</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ulrich+JD%22">Ulrich JD</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in Saint Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Peng+J%22">Peng J</searchLink>; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University in Saint Louis, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University in Saint Louis, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University in Saint Louis, St. Louis, MO, USA. Electronic address: holtzman@wustl.edu.
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  Data: <searchLink fieldCode="JN" term="%220376606%22">Journal of lipid research</searchLink> [J Lipid Res] 2026 Mar; Vol. 67 (3), pp. 101000. <i>Date of Electronic Publication: </i>2026 Feb 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0376606 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1539-7262 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222275%22">00222275 </searchLink><i>NLM ISO Abbreviation: </i>J Lipid Res <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jlr.2026.101000
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              Text: 2026 Mar
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