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STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model.

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Title: STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model.
Authors: Tripathi S; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Najem H; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Hurley L; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Du R; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Dmello C; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Ali H; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., McCortney K; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Habashy KJ; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Zhang P; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Horbinski CM; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Leoni L; Department of Radiology., Avery RJ; Department of Radiology., Lukas RV; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Neurology, and., Sita TL; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Raleigh DR; Department of Radiation Oncology, Neurological Surgery, and Pathology, University of California, San Francisco, San Francisco, California, USA., Sachdev S; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Stupp R; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Neurology, and., Lesniak MS; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Ashley DM; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Procissi D; Department of Radiology., Curran MA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Balyasnikova I; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center., Heimberger AB; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Feb 16; Vol. 136 (4). Date of Electronic Publication: 2026 Feb 16 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: STING-induced blood-brain barrier opening combined with radiotherapy potentiates antitumor response in a high-grade glioma model.
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  Data: <searchLink fieldCode="AU" term="%22Tripathi+S%22">Tripathi S</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Najem+H%22">Najem H</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Hurley+L%22">Hurley L</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Du+R%22">Du R</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Dmello+C%22">Dmello C</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Ali+H%22">Ali H</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22McCortney+K%22">McCortney K</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Habashy+KJ%22">Habashy KJ</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Horbinski+CM%22">Horbinski CM</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Leoni+L%22">Leoni L</searchLink>; Department of Radiology.<br /><searchLink fieldCode="AU" term="%22Avery+RJ%22">Avery RJ</searchLink>; Department of Radiology.<br /><searchLink fieldCode="AU" term="%22Lukas+RV%22">Lukas RV</searchLink>; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Neurology, and.<br /><searchLink fieldCode="AU" term="%22Sita+TL%22">Sita TL</searchLink>; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Raleigh+DR%22">Raleigh DR</searchLink>; Department of Radiation Oncology, Neurological Surgery, and Pathology, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Sachdev+S%22">Sachdev S</searchLink>; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Stupp+R%22">Stupp R</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.; Department of Neurology, and.<br /><searchLink fieldCode="AU" term="%22Lesniak+MS%22">Lesniak MS</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Ashley+DM%22">Ashley DM</searchLink>; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Procissi+D%22">Procissi D</searchLink>; Department of Radiology.<br /><searchLink fieldCode="AU" term="%22Curran+MA%22">Curran MA</searchLink>; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Balyasnikova+I%22">Balyasnikova I</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.<br /><searchLink fieldCode="AU" term="%22Heimberger+AB%22">Heimberger AB</searchLink>; Department of Neurological Surgery.; Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2026 Feb 16; Vol. 136 (4). <i>Date of Electronic Publication: </i>2026 Feb 16 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 16
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