Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population.

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Title: Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population.
Authors: Ohseto H; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan., Inoue K; Department of Health Promotion and Behavioral Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Takahashi I; Graduate School of Medicine, Tohoku University, Sendai, Japan., Obara T; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Tohoku University Hospital, Tohoku University, Sendai, Japan., Narita A; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Ishikuro M; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Orui M; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Murakami K; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Health and Social Behavior, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Noda A; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Tohoku University Hospital, Tohoku University, Sendai, Japan., Shinoda G; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Takase M; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Nakaya N; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Kogure M; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Hatanaka R; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Nakaya K; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Chiba I; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Tokioka S; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Kotozaki Y; Department of Hygiene and Preventive Medicine, Iwate Medical University, Iwate, Japan.; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan., Shimizu A; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan., Tanno K; Department of Hygiene and Preventive Medicine, Iwate Medical University, Iwate, Japan.; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan., Hozawa A; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan., Tamiya G; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; RIKEN Center for Advanced Intelligence Project, Tokyo, Japan., Kondo N; Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan., Kuriyama S; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.; Graduate School of Medicine, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.
Source: Translational psychiatry [Transl Psychiatry] 2026 Feb 17; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
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  Data: Genome-wide association study of social isolation in 63,497 Japanese individuals from the general population.
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  Data: <searchLink fieldCode="AU" term="%22Ohseto+H%22">Ohseto H</searchLink>; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+K%22">Inoue K</searchLink>; Department of Health Promotion and Behavioral Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+I%22">Takahashi I</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Obara+T%22">Obara T</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Tohoku University Hospital, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Narita+A%22">Narita A</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Ishikuro+M%22">Ishikuro M</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Orui+M%22">Orui M</searchLink>; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan.; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+K%22">Murakami K</searchLink>; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Department of Health and Social Behavior, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Noda+A%22">Noda A</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; Tohoku University Hospital, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Shinoda+G%22">Shinoda G</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Takase+M%22">Takase M</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Nakaya+N%22">Nakaya N</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Kogure+M%22">Kogure M</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Hatanaka+R%22">Hatanaka R</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Nakaya+K%22">Nakaya K</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Chiba+I%22">Chiba I</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Tokioka+S%22">Tokioka S</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Kotozaki+Y%22">Kotozaki Y</searchLink>; Department of Hygiene and Preventive Medicine, Iwate Medical University, Iwate, Japan.; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Shimizu+A%22">Shimizu A</searchLink>; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Tanno+K%22">Tanno K</searchLink>; Department of Hygiene and Preventive Medicine, Iwate Medical University, Iwate, Japan.; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan.<br /><searchLink fieldCode="AU" term="%22Hozawa+A%22">Hozawa A</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Tamiya+G%22">Tamiya G</searchLink>; Graduate School of Medicine, Tohoku University, Sendai, Japan.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.; RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+N%22">Kondo N</searchLink>; Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Kuriyama+S%22">Kuriyama S</searchLink>; International Research Institute of Disaster Science, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.; Graduate School of Medicine, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. shinichi.kuriyama.e6@tohoku.ac.jp.
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