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Serum Endogenous Opioid Levels are Associated with Self-Injury Severity in Adolescents with Non-Suicidal Self-Injury and Comorbid Depression.

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Title: Serum Endogenous Opioid Levels are Associated with Self-Injury Severity in Adolescents with Non-Suicidal Self-Injury and Comorbid Depression.
Authors: Ding JJ; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Liu XL; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China., Li A; Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong Key Laboratory of Non-human Primate Research, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China., Liang YY; Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong Key Laboratory of Non-human Primate Research, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China., Wang YB; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China., Zhu XN; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Li J; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Weng J; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Yan L; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Duan WW; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Zhang ZC; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China., Yuan TF; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China. tifeiyuan@163.com.; School of Psychology, Shanghai Jiaotong University, Shanghai, 200030, China. tifeiyuan@163.com., Guo XY; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China. xiaoyunguo@163.com., Zhou DS; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China. wyzhouds@sina.com.
Source: Neuroscience bulletin [Neurosci Bull] 2026 May; Vol. 42 (5), pp. 1177-1182. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Letter
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 101256850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-8218 (Electronic) Linking ISSN: 19958218 NLM ISO Abbreviation: Neurosci Bull Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Serum Endogenous Opioid Levels are Associated with Self-Injury Severity in Adolescents with Non-Suicidal Self-Injury and Comorbid Depression.
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  Data: <searchLink fieldCode="AU" term="%22Ding+JJ%22">Ding JJ</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Liu+XL%22">Liu XL</searchLink>; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong Key Laboratory of Non-human Primate Research, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Liang+YY%22">Liang YY</searchLink>; Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong Key Laboratory of Non-human Primate Research, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Wang+YB%22">Wang YB</searchLink>; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China.<br /><searchLink fieldCode="AU" term="%22Zhu+XN%22">Zhu XN</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Weng+J%22">Weng J</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Duan+WW%22">Duan WW</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Zhang+ZC%22">Zhang ZC</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China.<br /><searchLink fieldCode="AU" term="%22Yuan+TF%22">Yuan TF</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China. tifeiyuan@163.com.; School of Psychology, Shanghai Jiaotong University, Shanghai, 200030, China. tifeiyuan@163.com.<br /><searchLink fieldCode="AU" term="%22Guo+XY%22">Guo XY</searchLink>; Shanghai Key Laboratory of Psychotic Disorders, Brain Health Institute, National Center for Mental Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, 201108, China. xiaoyunguo@163.com.<br /><searchLink fieldCode="AU" term="%22Zhou+DS%22">Zhou DS</searchLink>; Department of Psychiatry, Zhejiang Key Laboratory of Drug Addiction & Brain Health, Affiliated Kangning Hospital of Ningbo University (Ningbo Kangning Hospital), Ningbo, 315201, China. wyzhouds@sina.com.
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  Data: <searchLink fieldCode="JN" term="%22101256850%22">Neuroscience bulletin</searchLink> [Neurosci Bull] 2026 May; Vol. 42 (5), pp. 1177-1182. <i>Date of Electronic Publication: </i>2026 Feb 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Singapore%22">Springer Singapore </searchLink><i>Country of Publication: </i>Singapore <i>NLM ID: </i>101256850 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1995-8218 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219958218%22">19958218 </searchLink><i>NLM ISO Abbreviation: </i>Neurosci Bull <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1007/s12264-026-01603-8
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        Text: English
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      – TitleFull: Serum Endogenous Opioid Levels are Associated with Self-Injury Severity in Adolescents with Non-Suicidal Self-Injury and Comorbid Depression.
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              Text: 2026 May
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