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Complement activation and M2-like macrophage accumulation in anti-MDA5 monoclonal antibody-induced hepatic injury in mice.

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Title: Complement activation and M2-like macrophage accumulation in anti-MDA5 monoclonal antibody-induced hepatic injury in mice.
Authors: Koga T; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Zaizen Y; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Suzuki H; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Sugi S; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Hozumi H; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan., Sakamoto N; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Suda T; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kusano H; Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan., Kawahara A; Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan., Akiba J; Department of Pathology, Kurume University School of Medicine, Kurume, Japan., Kawaguchi T; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Kaieda S; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Hoshino T; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.; Cancer Innovation Laboratory (CIL), Center for Cancer Research (CCR), National Cancer Institute (NCI)-Frederick, Frederick, MD, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 02; Vol. 17, pp. 1707202. Date of Electronic Publication: 2026 Feb 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Complement activation and M2-like macrophage accumulation in anti-MDA5 monoclonal antibody-induced hepatic injury in mice.
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  Data: <searchLink fieldCode="AU" term="%22Koga+T%22">Koga T</searchLink>; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Zaizen+Y%22">Zaizen Y</searchLink>; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+H%22">Suzuki H</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Sugi+S%22">Sugi S</searchLink>; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Hozumi+H%22">Hozumi H</searchLink>; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Sakamoto+N%22">Sakamoto N</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Suda+T%22">Suda T</searchLink>; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Mukae+H%22">Mukae H</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kusano+H%22">Kusano H</searchLink>; Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahara+A%22">Kawahara A</searchLink>; Department of Diagnostic Pathology, Kurume University Hospital, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Akiba+J%22">Akiba J</searchLink>; Department of Pathology, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+T%22">Kawaguchi T</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Kaieda+S%22">Kaieda S</searchLink>; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.<br /><searchLink fieldCode="AU" term="%22Hoshino+T%22">Hoshino T</searchLink>; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.; Cancer Innovation Laboratory (CIL), Center for Cancer Research (CCR), National Cancer Institute (NCI)-Frederick, Frederick, MD, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 02
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