Transcriptomics and metabolomics reveal the alleviating effect of lycopene on di-(2-ethylhexyl) phthalate-induced hepatotoxicity in mice.

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Title: Transcriptomics and metabolomics reveal the alleviating effect of lycopene on di-(2-ethylhexyl) phthalate-induced hepatotoxicity in mice.
Authors: Liu Y; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China; Minzhong Branch of Zhongshan Municipal Public Security Bureau, Zhongshan, Guangdong, China., Liu JL; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Chen LJ; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Hsu C; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Chen L; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Zeng JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li XW; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China., Yang JZ; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Xu JT; Department of Forensic Clinical Medicine, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: xjt3080@fimmu.edu.cn., Xie XL; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China. Electronic address: xiexiaoli1999@smu.edu.cn., Wang Q; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: wangqi1980@smu.edu.cn.
Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Jul; Vol. 153, pp. 110314. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1873-4847
DOI:10.1016/j.jnutbio.2026.110314