Transcriptomics and metabolomics reveal the alleviating effect of lycopene on di-(2-ethylhexyl) phthalate-induced hepatotoxicity in mice.

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Title: Transcriptomics and metabolomics reveal the alleviating effect of lycopene on di-(2-ethylhexyl) phthalate-induced hepatotoxicity in mice.
Authors: Liu Y; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China; Minzhong Branch of Zhongshan Municipal Public Security Bureau, Zhongshan, Guangdong, China., Liu JL; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Chen LJ; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Hsu C; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Chen L; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Zeng JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li XW; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China., Yang JZ; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Li JH; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China., Xu JT; Department of Forensic Clinical Medicine, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: xjt3080@fimmu.edu.cn., Xie XL; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China. Electronic address: xiexiaoli1999@smu.edu.cn., Wang Q; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: wangqi1980@smu.edu.cn.
Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Jul; Vol. 153, pp. 110314. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptomics and metabolomics reveal the alleviating effect of lycopene on di-(2-ethylhexyl) phthalate-induced hepatotoxicity in mice.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China; Minzhong Branch of Zhongshan Municipal Public Security Bureau, Zhongshan, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+JL%22">Liu JL</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chen+LJ%22">Chen LJ</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+JH%22">Li JH</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Hsu+C%22">Hsu C</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zeng+JH%22">Zeng JH</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+XW%22">Li XW</searchLink>; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yang+JZ%22">Yang JZ</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+JH%22">Li JH</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Xu+JT%22">Xu JT</searchLink>; Department of Forensic Clinical Medicine, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: xjt3080@fimmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xie+XL%22">Xie XL</searchLink>; Department of Toxicology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, China. Electronic address: xiexiaoli1999@smu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, Guangdong, China. Electronic address: wangqi1980@smu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229010081%22">The Journal of nutritional biochemistry</searchLink> [J Nutr Biochem] 2026 Jul; Vol. 153, pp. 110314. <i>Date of Electronic Publication: </i>2026 Feb 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9010081 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4847 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209552863%22">09552863 </searchLink><i>NLM ISO Abbreviation: </i>J Nutr Biochem <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul
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