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Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron-microglia co-culture model.

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Title: Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron-microglia co-culture model.
Authors: Siedlecki-Wullich D; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France. siedleckidolores@gmail.com., Ayral AM; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Iohan L; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Lemeu C; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Buiche V; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Blary K; Univ. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN - Institut d'Electronique de Microélectronique et de Nanotechnologie, Lille, F-59000, France., Chapuis J; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Eysert F; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Beury D; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France., Delacre M; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France., Hot D; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France., Masuda T; Division of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Knobeloch KP; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Prinz M; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; Center for Brain Research and Advancements In Neuroimmunology (BRAIN), Faculty of Medicine, University of Freiburg, Freiburg, 79106, Germany., Lambert JC; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France., Kilinc D; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France. devrim.kilinc@pasteur-lille.fr.
Source: Journal of neuroinflammation [J Neuroinflammation] 2026 Feb 19; Vol. 23 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron-microglia co-culture model.
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  Data: <searchLink fieldCode="AU" term="%22Siedlecki-Wullich+D%22">Siedlecki-Wullich D</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France. siedleckidolores@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ayral+AM%22">Ayral AM</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Iohan+L%22">Iohan L</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Lemeu+C%22">Lemeu C</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Buiche+V%22">Buiche V</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Blary+K%22">Blary K</searchLink>; Univ. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN - Institut d'Electronique de Microélectronique et de Nanotechnologie, Lille, F-59000, France.<br /><searchLink fieldCode="AU" term="%22Chapuis+J%22">Chapuis J</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Eysert+F%22">Eysert F</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Beury+D%22">Beury D</searchLink>; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France.<br /><searchLink fieldCode="AU" term="%22Delacre+M%22">Delacre M</searchLink>; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France.<br /><searchLink fieldCode="AU" term="%22Hot+D%22">Hot D</searchLink>; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, Lille, F-59000, France.<br /><searchLink fieldCode="AU" term="%22Masuda+T%22">Masuda T</searchLink>; Division of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Knobeloch+KP%22">Knobeloch KP</searchLink>; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Prinz+M%22">Prinz M</searchLink>; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; Center for Brain Research and Advancements In Neuroimmunology (BRAIN), Faculty of Medicine, University of Freiburg, Freiburg, 79106, Germany.<br /><searchLink fieldCode="AU" term="%22Lambert+JC%22">Lambert JC</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France.<br /><searchLink fieldCode="AU" term="%22Kilinc+D%22">Kilinc D</searchLink>; Université de Lille, Institut Pasteur de Lille, CHU Lille, INSERM U1167, LabEx DISTALZ, Lille, 59019, France. devrim.kilinc@pasteur-lille.fr.
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  Data: <searchLink fieldCode="JN" term="%22101222974%22">Journal of neuroinflammation</searchLink> [J Neuroinflammation] 2026 Feb 19; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101222974 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-2094 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217422094%22">17422094 </searchLink><i>NLM ISO Abbreviation: </i>J Neuroinflammation <i>Subsets: </i>MEDLINE
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