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New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project.

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Title: New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project.
Authors: Ardenkjær-Skinnerup J; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Baert Y; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium., Bajard L; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia., Blum J; SCAHT - Swiss Centre for Applied Human Toxicology and Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Brion F; Ecotoxicology of Substances and Environment Unit, National Institute for Industrial Environment and Risks, Verneuil-en-Halatte, France., Coppola L; Center for Gender-Specific Medicine, Italian National Institute of Health, Rome, Italy., Fini JB; PhyMA Laboratory, UMR7221, National Muséum of Natural History, Paris, France., Fritsche E; SCAHT - Swiss Centre for Applied Human Toxicology and Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Holbech H; Department of Biology, University of Southern Denmark, Odense, Denmark., Hurem S; Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway., Jacobs MN; Radiation, Chemical, Climate and Environmental Hazards Directorate, UK Health Security Agency, Chilton, United Kingdom., Johansson HKL; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Knapen D; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Koch K; IUF - Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.; DNTOX GmbH, Duesseldorf, Germany., Lyche JL; Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway., Mai PNT; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Neuhaus W; Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, Austria.; Faculty of Medicine and Dentistry, Danube Private University (DPU), Krems, Austria., Nikolov NG; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Nurani A; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Papageorgiou K; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium., Poulsen R; Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, Austria., Ramhøj L; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Řehůřková E; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia., Rosenmai AK; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Rüegg J; Department of Organismal Biology, Uppsala University, Uppsala, Sweden., Sovadinová I; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia., Tait S; Center for Gender-Specific Medicine, Italian National Institute of Health, Rome, Italy., Van de Pette M; Radiation, Chemical, Climate and Environmental Hazards Directorate, UK Health Security Agency, Chilton, United Kingdom., Vanhaecke T; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium., Vergauwen L; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Wedebye EB; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark., Xu EG; Department of Biology, University of Southern Denmark, Odense, Denmark., Svingen T; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Source: Frontiers in toxicology [Front Toxicol] 2026 Feb 03; Vol. 8, pp. 1736963. Date of Electronic Publication: 2026 Feb 03 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101777990 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-3080 (Electronic) Linking ISSN: 26733080 NLM ISO Abbreviation: Front Toxicol Subsets: PubMed not MEDLINE
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  Data: New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project.
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  Data: <searchLink fieldCode="AU" term="%22Ardenkjær-Skinnerup+J%22">Ardenkjær-Skinnerup J</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Baert+Y%22">Baert Y</searchLink>; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium.<br /><searchLink fieldCode="AU" term="%22Bajard+L%22">Bajard L</searchLink>; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Blum+J%22">Blum J</searchLink>; SCAHT - Swiss Centre for Applied Human Toxicology and Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brion+F%22">Brion F</searchLink>; Ecotoxicology of Substances and Environment Unit, National Institute for Industrial Environment and Risks, Verneuil-en-Halatte, France.<br /><searchLink fieldCode="AU" term="%22Coppola+L%22">Coppola L</searchLink>; Center for Gender-Specific Medicine, Italian National Institute of Health, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fini+JB%22">Fini JB</searchLink>; PhyMA Laboratory, UMR7221, National Muséum of Natural History, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fritsche+E%22">Fritsche E</searchLink>; SCAHT - Swiss Centre for Applied Human Toxicology and Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Holbech+H%22">Holbech H</searchLink>; Department of Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Hurem+S%22">Hurem S</searchLink>; Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.<br /><searchLink fieldCode="AU" term="%22Jacobs+MN%22">Jacobs MN</searchLink>; Radiation, Chemical, Climate and Environmental Hazards Directorate, UK Health Security Agency, Chilton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Johansson+HKL%22">Johansson HKL</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Knapen+D%22">Knapen D</searchLink>; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Koch+K%22">Koch K</searchLink>; IUF - Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.; DNTOX GmbH, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Lyche+JL%22">Lyche JL</searchLink>; Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.<br /><searchLink fieldCode="AU" term="%22Mai+PNT%22">Mai PNT</searchLink>; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Neuhaus+W%22">Neuhaus W</searchLink>; Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, Austria.; Faculty of Medicine and Dentistry, Danube Private University (DPU), Krems, Austria.<br /><searchLink fieldCode="AU" term="%22Nikolov+NG%22">Nikolov NG</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Nurani+A%22">Nurani A</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Papageorgiou+K%22">Papageorgiou K</searchLink>; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium.<br /><searchLink fieldCode="AU" term="%22Poulsen+R%22">Poulsen R</searchLink>; Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ramhøj+L%22">Ramhøj L</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Řehůřková+E%22">Řehůřková E</searchLink>; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Rosenmai+AK%22">Rosenmai AK</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Rüegg+J%22">Rüegg J</searchLink>; Department of Organismal Biology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Sovadinová+I%22">Sovadinová I</searchLink>; RECETOX, Faculty of Science, Masaryk University, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Tait+S%22">Tait S</searchLink>; Center for Gender-Specific Medicine, Italian National Institute of Health, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Van+de+Pette+M%22">Van de Pette M</searchLink>; Radiation, Chemical, Climate and Environmental Hazards Directorate, UK Health Security Agency, Chilton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vanhaecke+T%22">Vanhaecke T</searchLink>; Department of In Vitro Toxicology and Dermato-Cosmetology (IVTD), Vrije Universiteit Brussel, Jette, Belgium.<br /><searchLink fieldCode="AU" term="%22Vergauwen+L%22">Vergauwen L</searchLink>; Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Wedebye+EB%22">Wedebye EB</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Xu+EG%22">Xu EG</searchLink>; Department of Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Svingen+T%22">Svingen T</searchLink>; National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101777990%22">Frontiers in toxicology</searchLink> [Front Toxicol] 2026 Feb 03; Vol. 8, pp. 1736963. <i>Date of Electronic Publication: </i>2026 Feb 03 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101777990 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2673-3080 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226733080%22">26733080 </searchLink><i>NLM ISO Abbreviation: </i>Front Toxicol <i>Subsets: </i>PubMed not MEDLINE
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