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The novel second-generation triterpenoid SCY-247 maintains in vitro and in vivo activity against resistant Candida glabrata.

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Title: The novel second-generation triterpenoid SCY-247 maintains in vitro and in vivo activity against resistant Candida glabrata.
Authors: Wiederhold NP; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Najvar LK; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Jaramillo R; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Olivo M; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Patterson HP; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Patterson TF; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Apr; Vol. 70 (4), pp. e0162525. Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: The novel second-generation triterpenoid SCY-247 maintains in vitro and in vivo activity against resistant Candida glabrata.
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  Data: <searchLink fieldCode="AU" term="%22Wiederhold+NP%22">Wiederhold NP</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Najvar+LK%22">Najvar LK</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Jaramillo+R%22">Jaramillo R</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Olivo+M%22">Olivo M</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+HP%22">Patterson HP</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Patterson+TF%22">Patterson TF</searchLink>; University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2026 Apr; Vol. 70 (4), pp. e0162525. <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE
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        Value: 10.1128/aac.01625-25
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      – Code: eng
        Text: English
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              Text: 2026 Apr
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