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Potent and dose-sparing next-generation SARS-CoV-2 vaccine, mRNA-1283, induces polyfunctional and durable T cell immunity.

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Title: Potent and dose-sparing next-generation SARS-CoV-2 vaccine, mRNA-1283, induces polyfunctional and durable T cell immunity.
Authors: Paila YD; Moderna, Inc., Cambridge, MA, 02142, USA., Pajon R; Moderna, Inc., Cambridge, MA, 02142, USA., Banbury B; Adaptive Biotechnologies, Seattle, WA, 98109, USA., Fields P; Adaptive Biotechnologies, Seattle, WA, 98109, USA., Maglinao M; Moderna, Inc., Cambridge, MA, 02142, USA., De Rosa SC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA., Morris D; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA., McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA., Siangphoe U; Moderna, Inc., Cambridge, MA, 02142, USA., Cohen KW; Moderna, Inc., Cambridge, MA, 02142, USA. Kristen.Cohen@modernatx.com., Paris R; Moderna, Inc., Cambridge, MA, 02142, USA. robert.paris@modernatx.com.
Source: NPJ vaccines [NPJ Vaccines] 2026 Feb 19; Vol. 11 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Potent and dose-sparing next-generation SARS-CoV-2 vaccine, mRNA-1283, induces polyfunctional and durable T cell immunity.
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  Data: <searchLink fieldCode="AU" term="%22Paila+YD%22">Paila YD</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Pajon+R%22">Pajon R</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Banbury+B%22">Banbury B</searchLink>; Adaptive Biotechnologies, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Fields+P%22">Fields P</searchLink>; Adaptive Biotechnologies, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Maglinao+M%22">Maglinao M</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22De+Rosa+SC%22">De Rosa SC</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Morris+D%22">Morris D</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22McElrath+MJ%22">McElrath MJ</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, 98109, USA.; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Siangphoe+U%22">Siangphoe U</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+KW%22">Cohen KW</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA. Kristen.Cohen@modernatx.com.<br /><searchLink fieldCode="AU" term="%22Paris+R%22">Paris R</searchLink>; Moderna, Inc., Cambridge, MA, 02142, USA. robert.paris@modernatx.com.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2026 Feb 19; Vol. 11 (1). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41714624
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        Value: 10.1038/s41541-026-01402-2
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        Text: English
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              Text: 2026 Feb 19
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