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Indirect protection and long-term effectiveness of inactivated COVID-19 vaccine: a stepped-wedge randomised trial in Serrana, Brazil.

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Title: Indirect protection and long-term effectiveness of inactivated COVID-19 vaccine: a stepped-wedge randomised trial in Serrana, Brazil.
Authors: Borges MC; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil. marcosborges@fmrp.usp.br.; Clinical Research Center - S, São Paulo, SP, Brazil. marcosborges@fmrp.usp.br., Palacios R; Instituto Butantan, São Paulo, SP, Brazil., Conde MTRP; Instituto Butantan, São Paulo, SP, Brazil., Volpe GJ; Clinical Research Center - S, São Paulo, SP, Brazil., Ferreira NN; Clinical Research Center - S, São Paulo, SP, Brazil., Garibaldi PMM; Clinical Research Center - S, São Paulo, SP, Brazil., Fonseca BAL; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil., Calado RT; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil., Coutinho BM; Clinical Research Center - S, São Paulo, SP, Brazil., Gomes BBM; Clinical Research Center - S, São Paulo, SP, Brazil., de Lima Dias CFS; Clinical Research Center - S, São Paulo, SP, Brazil., de Moraes GR; Health Department, Serrana, SP, Brazil., Haddad SK; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil., de Miranda EJFP; Instituto Butantan, São Paulo, SP, Brazil., Braga PE; Instituto Butantan, São Paulo, SP, Brazil., Ragiotto L; Instituto Butantan, São Paulo, SP, Brazil., França JID; Instituto Butantan, São Paulo, SP, Brazil., de Lima MA; Instituto Butantan, São Paulo, SP, Brazil., de Oliveira Alves LB; Instituto Butantan, São Paulo, SP, Brazil., de Camargo Vieira Tenorio J; Instituto Butantan, São Paulo, SP, Brazil., Sampaio SC; Instituto Butantan, São Paulo, SP, Brazil., Covas DT; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.; Instituto Butantan, São Paulo, SP, Brazil., Dos Santos Almeida MAAL; Instituto Butantan, São Paulo, SP, Brazil., Morandi Junior E; Instituto Butantan, São Paulo, SP, Brazil., Boulos FC; Instituto Butantan, São Paulo, SP, Brazil.
Source: Scientific reports [Sci Rep] 2026 Feb 19; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Indirect protection and long-term effectiveness of inactivated COVID-19 vaccine: a stepped-wedge randomised trial in Serrana, Brazil.
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  Data: <searchLink fieldCode="AU" term="%22Borges+MC%22">Borges MC</searchLink>; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil. marcosborges@fmrp.usp.br.; Clinical Research Center - S, São Paulo, SP, Brazil. marcosborges@fmrp.usp.br.<br /><searchLink fieldCode="AU" term="%22Palacios+R%22">Palacios R</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Conde+MTRP%22">Conde MTRP</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Volpe+GJ%22">Volpe GJ</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+NN%22">Ferreira NN</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Garibaldi+PMM%22">Garibaldi PMM</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Fonseca+BAL%22">Fonseca BAL</searchLink>; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Calado+RT%22">Calado RT</searchLink>; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Coutinho+BM%22">Coutinho BM</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Gomes+BBM%22">Gomes BBM</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Lima+Dias+CFS%22">de Lima Dias CFS</searchLink>; Clinical Research Center - S, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Moraes+GR%22">de Moraes GR</searchLink>; Health Department, Serrana, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Haddad+SK%22">Haddad SK</searchLink>; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Miranda+EJFP%22">de Miranda EJFP</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Braga+PE%22">Braga PE</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Ragiotto+L%22">Ragiotto L</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22França+JID%22">França JID</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Lima+MA%22">de Lima MA</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+Alves+LB%22">de Oliveira Alves LB</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Camargo+Vieira+Tenorio+J%22">de Camargo Vieira Tenorio J</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Sampaio+SC%22">Sampaio SC</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Covas+DT%22">Covas DT</searchLink>; Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+Almeida+MAAL%22">Dos Santos Almeida MAAL</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Morandi+Junior+E%22">Morandi Junior E</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Boulos+FC%22">Boulos FC</searchLink>; Instituto Butantan, São Paulo, SP, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Feb 19; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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