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Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity.

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Title: Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity.
Authors: Sun H; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Mo L; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Cao M; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China., Tian Y; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Mo L; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Ni Z; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang S; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China., Huang X; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China., Wang Y; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Lam SM; Jiangsu Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases, LipidALL Technologies, Changzhou, 213022, China. smlam@lipidall.com.; Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, 510095, China. smlam@lipidall.com., Shui G; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China. ghshui@genetics.ac.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. ghshui@genetics.ac.cn.; Guangzhou National Laboratory, Guangzhou, 510005, China. ghshui@genetics.ac.cn.
Source: Journal of translational medicine [J Transl Med] 2026 Feb 19; Vol. 24 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity.
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  Data: <searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Mo+L%22">Mo L</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Cao+M%22">Cao M</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Mo+L%22">Mo L</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Ni+Z%22">Ni Z</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Lam+SM%22">Lam SM</searchLink>; Jiangsu Key Laboratory of Molecular Targets and Intervention for Metabolic Diseases, LipidALL Technologies, Changzhou, 213022, China. smlam@lipidall.com.; Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, 510095, China. smlam@lipidall.com.<br /><searchLink fieldCode="AU" term="%22Shui+G%22">Shui G</searchLink>; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China. ghshui@genetics.ac.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. ghshui@genetics.ac.cn.; Guangzhou National Laboratory, Guangzhou, 510005, China. ghshui@genetics.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Feb 19; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-07881-0
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      – TitleFull: Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity.
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              Text: 2026 Feb 19
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