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Dihydroartemisinin Alleviates Neuronal Damage and Seizures in Epileptic Mice by Inhibiting Ferroptosis via the SIRT1/FOXO1/SLC7A11/GPX4 Pathway.

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Title: Dihydroartemisinin Alleviates Neuronal Damage and Seizures in Epileptic Mice by Inhibiting Ferroptosis via the SIRT1/FOXO1/SLC7A11/GPX4 Pathway.
Authors: You Z; Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Huang C; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Gao X; Department of Anesthesiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Fan Z; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Wei F; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., He Y; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Zhao S; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Sun J; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 Feb; Vol. 32 (2), pp. e70798.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dihydroartemisinin Alleviates Neuronal Damage and Seizures in Epileptic Mice by Inhibiting Ferroptosis via the SIRT1/FOXO1/SLC7A11/GPX4 Pathway.
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  Data: <searchLink fieldCode="AU" term="%22You+Z%22">You Z</searchLink>; Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Anesthesiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Fan+Z%22">Fan Z</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Wei+F%22">Wei F</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
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      – TitleFull: Dihydroartemisinin Alleviates Neuronal Damage and Seizures in Epileptic Mice by Inhibiting Ferroptosis via the SIRT1/FOXO1/SLC7A11/GPX4 Pathway.
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              Text: 2026 Feb
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