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Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells.

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Title: Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells.
Authors: Michilli A; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy., Bassi C; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy., Moshiri F; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy., De Siena B; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy., Marinaro R; Center for Molecular Biology (CDBM), Ferrara University Hospital, 44124 Ferrara, Italy., Callegari E; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy., Negrini M; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy.; Center for Molecular Biology (CDBM), Ferrara University Hospital, 44124 Ferrara, Italy., Sabbioni S; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Source: Biotech (Basel (Switzerland)) [BioTech (Basel)] 2026 Feb 11; Vol. 15 (1). Date of Electronic Publication: 2026 Feb 11.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 9918383086206676 Publication Model: Electronic Cited Medium: Internet ISSN: 2673-6284 (Electronic) Linking ISSN: 26736284 NLM ISO Abbreviation: BioTech (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells.
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  Data: <searchLink fieldCode="AU" term="%22Michilli+A%22">Michilli A</searchLink>; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Bassi+C%22">Bassi C</searchLink>; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Moshiri+F%22">Moshiri F</searchLink>; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22De+Siena+B%22">De Siena B</searchLink>; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Marinaro+R%22">Marinaro R</searchLink>; Center for Molecular Biology (CDBM), Ferrara University Hospital, 44124 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Callegari+E%22">Callegari E</searchLink>; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Negrini+M%22">Negrini M</searchLink>; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy.; Center for Molecular Biology (CDBM), Ferrara University Hospital, 44124 Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Sabbioni+S%22">Sabbioni S</searchLink>; Department of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.; Laboratorio per le Tecnologie delle Terapie Avanzate (LTTA), University of Ferrara, 44121 Ferrara, Italy.
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  Data: <searchLink fieldCode="JN" term="%229918383086206676%22">Biotech (Basel (Switzerland))</searchLink> [BioTech (Basel)] 2026 Feb 11; Vol. 15 (1). <i>Date of Electronic Publication: </i>2026 Feb 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9918383086206676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2673-6284 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226736284%22">26736284 </searchLink><i>NLM ISO Abbreviation: </i>BioTech (Basel) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/biotech15010018
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      – TitleFull: Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells.
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              Text: 2026 Feb 11
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