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Nanoscopic tau aggregates are not shared intermediates but disease-specific entities across tauopathies.

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Title: Nanoscopic tau aggregates are not shared intermediates but disease-specific entities across tauopathies.
Authors: Böken D; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Huang M; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Wu Y; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Fertan E; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Cotton MW; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Meisl G; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Lam JYL; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK; Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China., Baig S; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Rowe JB; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, CB2 0SZ Cambridge, UK., Smith C; Department of Neuropathology, University of Edinburgh, EH4 2XU Edinburgh, UK., Quaegebeur A; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, CB2 0SZ Cambridge, UK., Cox D; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK; School of Sciences, University of Wollongong, Wollongong, NSW 2522, Australia., McEwan WA; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK., Klenerman D; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK. Electronic address: dk10012@cam.ac.uk.
Source: Cell reports [Cell Rep] 2026 Feb 24; Vol. 45 (2), pp. 116934. Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Böken+D%22">Böken D</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fertan+E%22">Fertan E</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cotton+MW%22">Cotton MW</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Meisl+G%22">Meisl G</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lam+JYL%22">Lam JYL</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK; Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Baig+S%22">Baig S</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, CB2 0SZ Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Smith+C%22">Smith C</searchLink>; Department of Neuropathology, University of Edinburgh, EH4 2XU Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Quaegebeur+A%22">Quaegebeur A</searchLink>; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, CB2 0SZ Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cox+D%22">Cox D</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK; School of Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.<br /><searchLink fieldCode="AU" term="%22McEwan+WA%22">McEwan WA</searchLink>; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+D%22">Klenerman D</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK; UK Dementia Research Institute, University of Cambridge, CB2 0AH Cambridge, UK. Electronic address: dk10012@cam.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 Feb 24; Vol. 45 (2), pp. 116934. <i>Date of Electronic Publication: </i>2026 Feb 19.
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