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UCP2 protects against intracerebral hemorrhage-induced ferroptosis via suppression of TRIM21-dependent GPX4.

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Title: UCP2 protects against intracerebral hemorrhage-induced ferroptosis via suppression of TRIM21-dependent GPX4.
Authors: Zhang RC; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China., Lu HB; Department of Neurology, Suqian Zhongwu Hospital, Suqian 223800, PR China., Zhu J; Department of Pathology, Xuzhou Medical University, Xuzhou 221004, PR China., Liu YW; Department of Human Anatomy, Xuzhou Medical University, Xuzhou 221004, PR China., Wang XY; Department of Pathology, Xuzhou Medical University, Xuzhou 221004, PR China., Shi Y; Department of Neurology, Xuzhou Cancer Hospital, Xuzhou 221018, PR China., Dai LL; Department of Radiology, Fengxian People's Hospital, Xuzhou 221700, PR China. Electronic address: 673588522@qq.com., Zhu SG; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China. Electronic address: Sgzhuxyfy@126.com., Cheng YB; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China. Electronic address: chengyb@xzhmu.edu.cn.
Source: Experimental neurology [Exp Neurol] 2026 Jun; Vol. 400, pp. 115691. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: UCP2 protects against intracerebral hemorrhage-induced ferroptosis via suppression of TRIM21-dependent GPX4.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+RC%22">Zhang RC</searchLink>; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China.<br /><searchLink fieldCode="AU" term="%22Lu+HB%22">Lu HB</searchLink>; Department of Neurology, Suqian Zhongwu Hospital, Suqian 223800, PR China.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Pathology, Xuzhou Medical University, Xuzhou 221004, PR China.<br /><searchLink fieldCode="AU" term="%22Liu+YW%22">Liu YW</searchLink>; Department of Human Anatomy, Xuzhou Medical University, Xuzhou 221004, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Pathology, Xuzhou Medical University, Xuzhou 221004, PR China.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Department of Neurology, Xuzhou Cancer Hospital, Xuzhou 221018, PR China.<br /><searchLink fieldCode="AU" term="%22Dai+LL%22">Dai LL</searchLink>; Department of Radiology, Fengxian People's Hospital, Xuzhou 221700, PR China. Electronic address: 673588522@qq.com.<br /><searchLink fieldCode="AU" term="%22Zhu+SG%22">Zhu SG</searchLink>; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China. Electronic address: Sgzhuxyfy@126.com.<br /><searchLink fieldCode="AU" term="%22Cheng+YB%22">Cheng YB</searchLink>; Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, PR China. Electronic address: chengyb@xzhmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%220370712%22">Experimental neurology</searchLink> [Exp Neurol] 2026 Jun; Vol. 400, pp. 115691. <i>Date of Electronic Publication: </i>2026 Feb 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370712 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2430 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200144886%22">00144886 </searchLink><i>NLM ISO Abbreviation: </i>Exp Neurol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.expneurol.2026.115691
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      – Code: eng
        Text: English
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        StartPage: 115691
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      – TitleFull: UCP2 protects against intracerebral hemorrhage-induced ferroptosis via suppression of TRIM21-dependent GPX4.
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            NameFull: Zhang RC
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            NameFull: Lu HB
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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            – TitleFull: Experimental neurology
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