Whole blood DNA methylation signature of epigenetic aging in medication overuse headache.

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Title: Whole blood DNA methylation signature of epigenetic aging in medication overuse headache.
Authors: Kwiatkowska KM; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy. katarzyn.kwiatkowsk2@unibo.it., Mascarella D; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy., Ferraresi F; Department of Chemistry 'Giacomo Ciamician', University of Bologna, 40126, Bologna, Italy., Pirazzini C; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy., Ravaioli F; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy., Bacalini MG; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy., Dall'Olio D; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy., Sala C; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy., Castellani G; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy., Calzari L; Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, 20095, Milan, Italy., Gentilini D; Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, 20095, Milan, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, 27100, Pavia, Italy., Terlizzi R; U. O. Neurologia, Ospedale Bufalini, Cesena, Italy., Pierangeli G; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy., Cortelli P; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy., Favoni V; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy., Garagnani P; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy. paolo.garagnani2@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy. paolo.garagnani2@unibo.it., Cevoli S; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy. sabina.cevoli@unibo.it.
Source: The journal of headache and pain [J Headache Pain] 2026 Feb 20; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Whole blood DNA methylation signature of epigenetic aging in medication overuse headache.
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  Data: <searchLink fieldCode="AU" term="%22Kwiatkowska+KM%22">Kwiatkowska KM</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy. katarzyn.kwiatkowsk2@unibo.it.<br /><searchLink fieldCode="AU" term="%22Mascarella+D%22">Mascarella D</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ferraresi+F%22">Ferraresi F</searchLink>; Department of Chemistry 'Giacomo Ciamician', University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Pirazzini+C%22">Pirazzini C</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ravaioli+F%22">Ravaioli F</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Bacalini+MG%22">Bacalini MG</searchLink>; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Dall'Olio+D%22">Dall'Olio D</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Sala+C%22">Sala C</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Castellani+G%22">Castellani G</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Calzari+L%22">Calzari L</searchLink>; Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, 20095, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gentilini+D%22">Gentilini D</searchLink>; Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, 20095, Milan, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, 27100, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Terlizzi+R%22">Terlizzi R</searchLink>; U. O. Neurologia, Ospedale Bufalini, Cesena, Italy.<br /><searchLink fieldCode="AU" term="%22Pierangeli+G%22">Pierangeli G</searchLink>; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Cortelli+P%22">Cortelli P</searchLink>; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Favoni+V%22">Favoni V</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Garagnani+P%22">Garagnani P</searchLink>; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy. paolo.garagnani2@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy. paolo.garagnani2@unibo.it.<br /><searchLink fieldCode="AU" term="%22Cevoli+S%22">Cevoli S</searchLink>; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy. sabina.cevoli@unibo.it.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2026 Feb 20; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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