Integrated infectious disease and substance use disorder treatment for severe injection-related infections: protocol for the randomized controlled HI-SIRI trial.

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Title: Integrated infectious disease and substance use disorder treatment for severe injection-related infections: protocol for the randomized controlled HI-SIRI trial.
Authors: Serota DP; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA. dserota@med.miami.edu., Feaster DJ; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Bartholomew TS; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Kapadia SN; Division of Infectious Diseases, Weill Cornell Medicine, New York City, NY, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York City, NY, USA., Gooden LK; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA., Murphy SM; Department of Population Health Sciences, Weill Cornell Medicine, New York City, NY, USA., Malik S; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA., Chueng TA; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA., Hernandez S; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA., Rodriguez AE; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA., Alonso E; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Horigian VE; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Walker R; The Emmes Company, Rockville, MD, USA., Matheson T; San Francisco Dept of Public Health, San Francisco, CA, USA., Moran LM; Center for the Clinical Trials Network, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA., Nelson CM; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA., Parish C; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA., Tookes HE; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA., Rio CD; Division of Infectious Diseases , Department of Medicine, Emory University , Atlanta, GA, USA., Metsch LR; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA.
Source: Addiction science & clinical practice [Addict Sci Clin Pract] 2026 Feb 21; Vol. 21 (1). Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101316917 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-0640 (Electronic) Linking ISSN: 19400632 NLM ISO Abbreviation: Addict Sci Clin Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated infectious disease and substance use disorder treatment for severe injection-related infections: protocol for the randomized controlled HI-SIRI trial.
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  Data: <searchLink fieldCode="AU" term="%22Serota+DP%22">Serota DP</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA. dserota@med.miami.edu.<br /><searchLink fieldCode="AU" term="%22Feaster+DJ%22">Feaster DJ</searchLink>; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bartholomew+TS%22">Bartholomew TS</searchLink>; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Kapadia+SN%22">Kapadia SN</searchLink>; Division of Infectious Diseases, Weill Cornell Medicine, New York City, NY, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gooden+LK%22">Gooden LK</searchLink>; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA.<br /><searchLink fieldCode="AU" term="%22Murphy+SM%22">Murphy SM</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Malik+S%22">Malik S</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Chueng+TA%22">Chueng TA</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+S%22">Hernandez S</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+AE%22">Rodriguez AE</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Alonso+E%22">Alonso E</searchLink>; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Horigian+VE%22">Horigian VE</searchLink>; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Walker+R%22">Walker R</searchLink>; The Emmes Company, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Matheson+T%22">Matheson T</searchLink>; San Francisco Dept of Public Health, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Moran+LM%22">Moran LM</searchLink>; Center for the Clinical Trials Network, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+CM%22">Nelson CM</searchLink>; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Parish+C%22">Parish C</searchLink>; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA.<br /><searchLink fieldCode="AU" term="%22Tookes+HE%22">Tookes HE</searchLink>; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St, Suite 851, Miami FL, 33136, USA.<br /><searchLink fieldCode="AU" term="%22Rio+CD%22">Rio CD</searchLink>; Division of Infectious Diseases , Department of Medicine, Emory University , Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Metsch+LR%22">Metsch LR</searchLink>; Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York City NY , USA.
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  Data: <searchLink fieldCode="JN" term="%22101316917%22">Addiction science & clinical practice</searchLink> [Addict Sci Clin Pract] 2026 Feb 21; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Feb 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101316917 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1940-0640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219400632%22">19400632 </searchLink><i>NLM ISO Abbreviation: </i>Addict Sci Clin Pract <i>Subsets: </i>MEDLINE
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