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Genomic insights into substance use and disinhibitory disorders.

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Title: Genomic insights into substance use and disinhibitory disorders.
Authors: Williams CM; Laboratoire de Sciences Cognitives et Psycholinguistique, Département d'Études Cognitives, École Normale Supérieure, EHESS, CNRS, PSL University, Paris, France.; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA., Poore HE; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA., Londono-Correa D; Department of Psychology, University of Texas at Austin, Austin, TX, USA., Ning Y; Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands.; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Courchesne-Krak NS; Department of Psychiatry, University of California, San Diego, CA, USA., Choi M; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA.; Department of Psychology, School of Arts and Sciences, Rutgers University, NJ, USA., Tubbs JD; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA., Rosenblatt M; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Tanksley PT; ALERRT Center, Texas State University, San Marcos, TX, USA., Aliev F; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA., Bell NY; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Deak JD; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA., Gonzalez J; Department of Psychiatry, University of California, San Diego, CA, USA., Jennings M; Department of Psychiatry, University of California, San Diego, CA, USA., Johnson EC; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Phung TN; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Schipper M; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., de Vlaming R; Department of Econometrics and Data Science, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Yuan K; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Zhou H; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA., Balcke E; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA., Brislin SJ; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA., de la Fuente J; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.; Center on Aging and Population Sciences, University of Texas at Austin, Austin, TX, USA., Gandal MJ; Lifespan Brain Institute at Penn Med and the Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA., Ge T; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA., Gelernter J; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Genetics, Yale School of Medicine, New Haven, CT, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Smoller JW; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA., Tucker-Drob EM; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.; Center on Aging and Population Sciences, University of Texas at Austin, Austin, TX, USA., Waldman ID; Department of Psychology, Emory University, Atlanta, GA, USA., Palmer AA; Department of Psychiatry, University of California, San Diego, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, CA, USA., Barr PB; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA.; Department of Community Health Sciences, School of Public Health, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA.; Institute for Genomics in Health, State University of New York Downstate Health Sciences University, Brooklyn, NY, USA.; VA New York Harbor Healthcare System, Brooklyn, NY, USA., Sanchez-Roige S; Department of Psychiatry, University of California, San Diego, CA, USA.; Institute for Genomic Medicine, University of California, San Diego, CA, USA.; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Linnér RK; Department of Economics, Leiden Law School, Universiteit Leiden, Leiden, The Netherlands., Dick DM; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA., Harden KP; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA., Mallard TT; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA.
Corporate Authors: COGA Collaborators
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Feb 09. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: <searchLink fieldCode="AU" term="%22Williams+CM%22">Williams CM</searchLink>; Laboratoire de Sciences Cognitives et Psycholinguistique, Département d'Études Cognitives, École Normale Supérieure, EHESS, CNRS, PSL University, Paris, France.; Department of Psychology, University of Texas at Austin, Austin, TX, USA.; Population Research Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Poore+HE%22">Poore HE</searchLink>; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Londono-Correa+D%22">Londono-Correa D</searchLink>; Department of Psychology, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ning+Y%22">Ning Y</searchLink>; Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands.; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Courchesne-Krak+NS%22">Courchesne-Krak NS</searchLink>; 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Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Balcke+E%22">Balcke E</searchLink>; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; Rutgers Addiction Research Center, Brain Health Institute, Rutgers Health, Piscataway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Brislin+SJ%22">Brislin SJ</searchLink>; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.; 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