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S-nitrosoglutathione reductase GSNOR drives age-related obesity by promoting adipose tissue whitening through de-nitrosation of Beclin-1.

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Title: S-nitrosoglutathione reductase GSNOR drives age-related obesity by promoting adipose tissue whitening through de-nitrosation of Beclin-1.
Authors: Qiao X; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Xie T; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Zhang Y; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Sun C; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Wu X; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Chen Y; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Yao Q; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Shi H; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Li S; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Zhao H; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Wang T; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Meng J; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China., Zhou L; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China., Niu M; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China., Hu Y; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China., Liu H; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China., Chen C; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China. changchen@ibp.ac.cn.; University of Chinese Academy of Sciences, Beijing, PR China. changchen@ibp.ac.cn.
Source: Nature communications [Nat Commun] 2026 Feb 23; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: S-nitrosoglutathione reductase GSNOR drives age-related obesity by promoting adipose tissue whitening through de-nitrosation of Beclin-1.
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  Data: <searchLink fieldCode="AU" term="%22Qiao+X%22">Qiao X</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Xie+T%22">Xie T</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Yao+Q%22">Yao Q</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Meng+J%22">Meng J</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Niu+M%22">Niu M</searchLink>; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Gastrointestinal Metabolic Surgery, Zhengzhou Central Hospital affiliated to Zhengzhou University, Zhengzhou, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; State Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China. changchen@ibp.ac.cn.; University of Chinese Academy of Sciences, Beijing, PR China. changchen@ibp.ac.cn.
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