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Solithromycin mitigates Prevotella intermedia-induced methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia by enhancing alveolar macrophage function.

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Title: Solithromycin mitigates Prevotella intermedia-induced methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia by enhancing alveolar macrophage function.
Authors: Fukushima K; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Iwanaga N; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Ashizawa N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Takeda K; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Hirayama T; Department of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Yoshida M; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Ide S; Infectious Diseases Experts Training Center, Nagasaki University Hospital, Nagasaki, Japan., Takazono T; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kosai K; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Sakamoto N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Naito M; Department of Microbiology and Oral Infection, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Yanagihara K; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 Feb 09; Vol. 16, pp. 1723186. Date of Electronic Publication: 2026 Feb 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Solithromycin mitigates Prevotella intermedia-induced methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia by enhancing alveolar macrophage function.
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  Data: <searchLink fieldCode="AU" term="%22Fukushima+K%22">Fukushima K</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Iwanaga+N%22">Iwanaga N</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Ashizawa+N%22">Ashizawa N</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+K%22">Takeda K</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Hirayama+T%22">Hirayama T</searchLink>; Department of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+M%22">Yoshida M</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Ide+S%22">Ide S</searchLink>; Infectious Diseases Experts Training Center, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takazono+T%22">Takazono T</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kosai+K%22">Kosai K</searchLink>; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Sakamoto+N%22">Sakamoto N</searchLink>; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Naito+M%22">Naito M</searchLink>; Department of Microbiology and Oral Infection, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagihara+K%22">Yanagihara K</searchLink>; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Mukae+H%22">Mukae H</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101585359%22">Frontiers in cellular and infection microbiology</searchLink> [Front Cell Infect Microbiol] 2026 Feb 09; Vol. 16, pp. 1723186. <i>Date of Electronic Publication: </i>2026 Feb 09 (<i>Print Publication: </i>2026).
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