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MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.

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Title: MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.
Authors: Nho RS; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Nielsen L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Roberts J; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Diep S, Taylor A; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Hager K; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Yengo R; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Rosas L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Farkas L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Prasad J; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Mebratu YA; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Rojas M; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH., Chan SY; Department of Medicine, University of Pittsburgh, Pittsburgh, 15261, PA., Horowitz JC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.
Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2026 Feb 12. Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 8917225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE
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  Data: MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.
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  Data: <searchLink fieldCode="AU" term="%22Nho+RS%22">Nho RS</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Nielsen+L%22">Nielsen L</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Roberts+J%22">Roberts J</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Diep+S%22">Diep S</searchLink><br /><searchLink fieldCode="AU" term="%22Taylor+A%22">Taylor A</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Hager+K%22">Hager K</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Yengo+R%22">Yengo R</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Rosas+L%22">Rosas L</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Farkas+L%22">Farkas L</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Prasad+J%22">Prasad J</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Mebratu+YA%22">Mebratu YA</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Rojas+M%22">Rojas M</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.<br /><searchLink fieldCode="AU" term="%22Chan+SY%22">Chan SY</searchLink>; Department of Medicine, University of Pittsburgh, Pittsburgh, 15261, PA.<br /><searchLink fieldCode="AU" term="%22Horowitz+JC%22">Horowitz JC</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, OH.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Thoracic+Society%22">American Thoracic Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8917225 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-4989 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210441549%22">10441549 </searchLink><i>NLM ISO Abbreviation: </i>Am J Respir Cell Mol Biol <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 12
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