A real-world comparison of nivolumab plus cabozantinib and pembrolizumab plus lenvatinib focusing on safety outcomes in metastatic renal cell carcinoma: results from the JK-FOOT consortium.

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Title: A real-world comparison of nivolumab plus cabozantinib and pembrolizumab plus lenvatinib focusing on safety outcomes in metastatic renal cell carcinoma: results from the JK-FOOT consortium.
Authors: Yanagisawa T; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan. t.yanagisawa.jikei@gmail.com.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. t.yanagisawa.jikei@gmail.com., Mori K; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria., Kawada T; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Katayama S; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Tsujino T; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan., Maenosono R; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan., Toyoda S; Department of Urology, Faculty of Medicine, Kindai University, Higashi-osaka, Japan., Nukaya T; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Japan., Morinaka H; Department of Urology, Kawasaki Medical School, Kurashiki, Japan., Tamura K; Department of Urology, Hamamatsu Medical University, Hamamatsu, Japan., Fukuokaya W; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan., Urabe F; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan., Murakami M; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan., Bekku K; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Takahara K; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Japan., Fujita K; Department of Urology, Faculty of Medicine, Kindai University, Higashi-osaka, Japan., Azuma H; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan., Araki M; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Inamoto T; Department of Urology, Hamamatsu Medical University, Hamamatsu, Japan., Komura K; Department of Urology, Kawasaki Medical School, Kurashiki, Japan., Kimura T; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.
Corporate Authors: JK-FOOT study group
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Feb 25; Vol. 75 (3). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article; Comparative Study; Multicenter Study
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A real-world comparison of nivolumab plus cabozantinib and pembrolizumab plus lenvatinib focusing on safety outcomes in metastatic renal cell carcinoma: results from the JK-FOOT consortium.
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  Data: <searchLink fieldCode="AU" term="%22Yanagisawa+T%22">Yanagisawa T</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan. t.yanagisawa.jikei@gmail.com.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. t.yanagisawa.jikei@gmail.com.<br /><searchLink fieldCode="AU" term="%22Mori+K%22">Mori K</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kawada+T%22">Kawada T</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Katayama+S%22">Katayama S</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujino+T%22">Tsujino T</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.<br /><searchLink fieldCode="AU" term="%22Maenosono+R%22">Maenosono R</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.<br /><searchLink fieldCode="AU" term="%22Toyoda+S%22">Toyoda S</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, Higashi-osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nukaya+T%22">Nukaya T</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Japan.<br /><searchLink fieldCode="AU" term="%22Morinaka+H%22">Morinaka H</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Tamura+K%22">Tamura K</searchLink>; Department of Urology, Hamamatsu Medical University, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Fukuokaya+W%22">Fukuokaya W</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.<br /><searchLink fieldCode="AU" term="%22Urabe+F%22">Urabe F</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+M%22">Murakami M</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.<br /><searchLink fieldCode="AU" term="%22Bekku+K%22">Bekku K</searchLink>; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Takahara+K%22">Takahara K</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+K%22">Fujita K</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, Higashi-osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+H%22">Azuma H</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.<br /><searchLink fieldCode="AU" term="%22Araki+M%22">Araki M</searchLink>; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Inamoto+T%22">Inamoto T</searchLink>; Department of Urology, Hamamatsu Medical University, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+K%22">Komura K</searchLink>; Department of Urology, Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+T%22">Kimura T</searchLink>; Department of Urology, The Jikei University School of Medicine, Nishi-Shimbashi, Japan.
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