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Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves.

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Title: Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves.
Authors: Thim T; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Nissen H; Department of Cardiology, Odense University Hospital, Odense, Denmark., Niemelä M; Department of Cardiology, Oulu University Hospital, Oulu, Finland; Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu, Oulu, Finland., Eftekhari A; Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark., Jalanko M; Department of Cardiology, Helsinki University Hospital, Helsinki, Finland., Savontaus M; Heart Center, Turku University Hospital, Turku, Finland., Jääskeläinen P; Heart Center, Kuopio University Hospital, Kuopio, Finland., Hensey M; Department of Cardiology, St James's Hospital, Dublin, Ireland., Jensen RV; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark., Nørgaard BL; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Frederiksen CA; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Vase HØ; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark., Pedersen L; Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark., Sørensen HT; Department of Clinical Epidemiology, Center for Population Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark., Christiansen EH; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Terkelsen CJ; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address: chriterk@rm.dk.
Source: American heart journal [Am Heart J] 2026 Jul; Vol. 297, pp. 107387. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article; Comparative Study; Randomized Controlled Trial
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves.
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  Data: <searchLink fieldCode="AU" term="%22Thim+T%22">Thim T</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Nissen+H%22">Nissen H</searchLink>; Department of Cardiology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Niemelä+M%22">Niemelä M</searchLink>; Department of Cardiology, Oulu University Hospital, Oulu, Finland; Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Eftekhari+A%22">Eftekhari A</searchLink>; Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Jalanko+M%22">Jalanko M</searchLink>; Department of Cardiology, Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Savontaus+M%22">Savontaus M</searchLink>; Heart Center, Turku University Hospital, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Jääskeläinen+P%22">Jääskeläinen P</searchLink>; Heart Center, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Hensey+M%22">Hensey M</searchLink>; Department of Cardiology, St James's Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Jensen+RV%22">Jensen RV</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Nørgaard+BL%22">Nørgaard BL</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Frederiksen+CA%22">Frederiksen CA</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Vase+HØ%22">Vase HØ</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+L%22">Pedersen L</searchLink>; Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Sørensen+HT%22">Sørensen HT</searchLink>; Department of Clinical Epidemiology, Center for Population Medicine, Aarhus University Hospital and Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Christiansen+EH%22">Christiansen EH</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Terkelsen+CJ%22">Terkelsen CJ</searchLink>; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address: chriterk@rm.dk.
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  Data: <searchLink fieldCode="JN" term="%220370465%22">American heart journal</searchLink> [Am Heart J] 2026 Jul; Vol. 297, pp. 107387. <i>Date of Electronic Publication: </i>2026 Feb 23.
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              Text: 2026 Jul
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