The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction.

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Bibliographic Details
Title: The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction.
Authors: Ritacco DA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Shahnawaz H; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Oduguwa A; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Hawk J; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Vizcaino B; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Farber DL; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA; Department of Surgery, Columbia University Irving Medical Center, New York, NY‬, USA., Gaudet RG; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: rg3477@cumc.columbia.edu.
Source: Molecular cell [Mol Cell] 2026 Mar 19; Vol. 86 (6), pp. 1116-1133.e8. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4164
DOI:10.1016/j.molcel.2026.01.029