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The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction.

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Title: The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction.
Authors: Ritacco DA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Shahnawaz H; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Oduguwa A; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Hawk J; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Vizcaino B; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Farber DL; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA; Department of Surgery, Columbia University Irving Medical Center, New York, NY‬, USA., Gaudet RG; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: rg3477@cumc.columbia.edu.
Source: Molecular cell [Mol Cell] 2026 Mar 19; Vol. 86 (6), pp. 1116-1133.e8. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction.
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  Data: <searchLink fieldCode="AU" term="%22Ritacco+DA%22">Ritacco DA</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shahnawaz+H%22">Shahnawaz H</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Oduguwa+A%22">Oduguwa A</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hawk+J%22">Hawk J</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Vizcaino+B%22">Vizcaino B</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Farber+DL%22">Farber DL</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA; Department of Surgery, Columbia University Irving Medical Center, New York, NY‬, USA.<br /><searchLink fieldCode="AU" term="%22Gaudet+RG%22">Gaudet RG</searchLink>; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: rg3477@cumc.columbia.edu.
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  Data: <searchLink fieldCode="JN" term="%229802571%22">Molecular cell</searchLink> [Mol Cell] 2026 Mar 19; Vol. 86 (6), pp. 1116-1133.e8. <i>Date of Electronic Publication: </i>2026 Feb 24.
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        Value: 10.1016/j.molcel.2026.01.029
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              Text: 2026 Mar 19
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