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Effectiveness of a digital clinical decision support algorithm for guiding antibiotic prescribing in pediatric outpatient care in Rwanda: A pragmatic cluster non-randomized controlled trial.

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Title: Effectiveness of a digital clinical decision support algorithm for guiding antibiotic prescribing in pediatric outpatient care in Rwanda: A pragmatic cluster non-randomized controlled trial.
Authors: Kulinkina AV; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Rwandarwacu VP; Swiss Tropical and Public Health Institute, Kigali, Rwanda., Habakurama J; Swiss Tropical and Public Health Institute, Kigali, Rwanda., Cobuccio L; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Norris M; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Kalisa E; Swiss Tropical and Public Health Institute, Kigali, Rwanda., Havugimana C; Swiss Tropical and Public Health Institute, Kigali, Rwanda., Ingabire A; Swiss Tropical and Public Health Institute, Kigali, Rwanda., Levine GA; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Tan R; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Faivre V; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Vonlanthen A; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Le Pogam MA; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland., Wyss K; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Tuyisenge L; Rwanda Pediatric Association, Kigali, Rwanda., Ngabonziza JCS; Rwanda Biomedical Center, Kigali, Rwanda.; University of Rwanda, Kigali, Rwanda., D'Acremont V; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
Source: PLoS medicine [PLoS Med] 2026 Feb 26; Vol. 23 (2), pp. e1004692. Date of Electronic Publication: 2026 Feb 26 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Effectiveness of a digital clinical decision support algorithm for guiding antibiotic prescribing in pediatric outpatient care in Rwanda: A pragmatic cluster non-randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Kulinkina+AV%22">Kulinkina AV</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rwandarwacu+VP%22">Rwandarwacu VP</searchLink>; Swiss Tropical and Public Health Institute, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Habakurama+J%22">Habakurama J</searchLink>; Swiss Tropical and Public Health Institute, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Cobuccio+L%22">Cobuccio L</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Norris+M%22">Norris M</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kalisa+E%22">Kalisa E</searchLink>; Swiss Tropical and Public Health Institute, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Havugimana+C%22">Havugimana C</searchLink>; Swiss Tropical and Public Health Institute, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Ingabire+A%22">Ingabire A</searchLink>; Swiss Tropical and Public Health Institute, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Levine+GA%22">Levine GA</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tan+R%22">Tan R</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Faivre+V%22">Faivre V</searchLink>; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vonlanthen+A%22">Vonlanthen A</searchLink>; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Le+Pogam+MA%22">Le Pogam MA</searchLink>; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wyss+K%22">Wyss K</searchLink>; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tuyisenge+L%22">Tuyisenge L</searchLink>; Rwanda Pediatric Association, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22Ngabonziza+JCS%22">Ngabonziza JCS</searchLink>; Rwanda Biomedical Center, Kigali, Rwanda.; University of Rwanda, Kigali, Rwanda.<br /><searchLink fieldCode="AU" term="%22D'Acremont+V%22">D'Acremont V</searchLink>; Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101231360%22">PLoS medicine</searchLink> [PLoS Med] 2026 Feb 26; Vol. 23 (2), pp. e1004692. <i>Date of Electronic Publication: </i>2026 Feb 26 (<i>Print Publication: </i>2026).
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