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Recommendations from the 2nd Consensus Workshop on Analytical Treatment Interruption in HIV Research Trials.

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Title: Recommendations from the 2nd Consensus Workshop on Analytical Treatment Interruption in HIV Research Trials.
Authors: Ndung'u T; Africa Health Research Institute, Durban, South Africa; Division of Infection and Immunity, University College London, London, UK; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa. Electronic address: thumbi.ndungu@ahri.org., Dong KL; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; Harvard Medical School, Cambridge, MA, USA; Infectious Diseases Division, Massachusetts General Hospital, Boston, MA, USA., Colby DJ; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Deeks SG; Division of HIV, Infectious Diseases & Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Cotton MF; Family Center for Clinical Research with Ubuntu, Department of Paediatrics and Child Health, Tygerberg Academic Hospital, Stellenbosch University, Cape Town, South Africa., Dubé K; Division of Infectious Diseases and Global Public Health, School of Medicine, University of California, San Diego, San Diego, CA, USA., Goulder PJ; Africa Health Research Institute, Durban, South Africa; Division of Infection and Immunity, University College London, London, UK; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; Department of Paediatrics, Oxford University, Oxford, UK., Julg B; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; Harvard Medical School, Cambridge, MA, USA., Nsubuga M; Joint Adherent Brothers and Sisters Against AIDS, Kampala, Uganda., Ajibola G; Botswana Harvard Health Partnership, Gaborone, Botswana., Bar KJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bengu N; Umkhuseli Innovation and Research Management, Durban, South Africa., Bwakura-Dangarembizi M; Department of Paediatrics and Child Health, University of Zimbabwe, Harare, Zimbabwe., Caskey M; Laboratory of Molecular Immunology, Rockefeller University, New York, NY, USA., Cromhout G; Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa., Kekitiinwa AR; Baylor College of Medicine Children's Foundation, Kampala, Uganda., Kilembe W; Center for Family Health Research, Lusaka, Zambia., Kuhn L; Gertrude H Sergievsky Center, Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA., Likhitwonnawut U; Thailand National CAB, Chiang Mai, Thailand., Mgodi NM; University of Zimbabwe Clinical Trials Research Centre, Harare, Zimbabwe., Persaud D; Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Peluso MJ; Division of HIV, Infectious Diseases & Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Rasmussen TA; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University, Aarhus, Denmark., Romo M; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Sacdalan C; SEARCH Research Foundation, Bangkok, Thailand; Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Samaneka W; University of Zimbabwe Clinical Trials Research Centre, Harare, Zimbabwe., Shapiro R; Department of Immunology and Infectious Diseases, Harvard T H Chan School of Public Health, Boston, MA, USA., Søgaard OS; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University, Aarhus, Denmark., Tudor-Williams G; Department of Infectious Diseases and Centre for Paediatrics and Child Health, Imperial College London, London, UK., Wambui C; Moi University Clinical Research Centre, Eldoret, Kenya., Tressler R; Division of AIDS, National Institute of Allergy and Infectious Diseases; National Institutes of Health, Bethesda, MD, USA., Lewin SR; Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Crowell TA; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Kasprowicz VO; Africa Health Research Institute, Durban, South Africa; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa., Trautmann L; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: ltrautmann@Global-ID.org.
Corporate Authors: 2nd ATI Consensus Workshop
Source: The lancet. HIV [Lancet HIV] 2026 Apr; Vol. 13 (4), pp. e271-e281. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article; Consensus Statement; Review
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101645355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3018 (Electronic) Linking ISSN: 23523018 NLM ISO Abbreviation: Lancet HIV Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Recommendations from the 2nd Consensus Workshop on Analytical Treatment Interruption in HIV Research Trials.
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  Data: <searchLink fieldCode="AU" term="%22Ndung'u+T%22">Ndung'u T</searchLink>; Africa Health Research Institute, Durban, South Africa; Division of Infection and Immunity, University College London, London, UK; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa. Electronic address: thumbi.ndungu@ahri.org.<br /><searchLink fieldCode="AU" term="%22Dong+KL%22">Dong KL</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; Harvard Medical School, Cambridge, MA, USA; Infectious Diseases Division, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Colby+DJ%22">Colby DJ</searchLink>; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Deeks+SG%22">Deeks SG</searchLink>; Division of HIV, Infectious Diseases & Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cotton+MF%22">Cotton MF</searchLink>; Family Center for Clinical Research with Ubuntu, Department of Paediatrics and Child Health, Tygerberg Academic Hospital, Stellenbosch University, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Dubé+K%22">Dubé K</searchLink>; Division of Infectious Diseases and Global Public Health, School of Medicine, University of California, San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goulder+PJ%22">Goulder PJ</searchLink>; Africa Health Research Institute, Durban, South Africa; Division of Infection and Immunity, University College London, London, UK; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; Department of Paediatrics, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Julg+B%22">Julg B</searchLink>; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; Harvard Medical School, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nsubuga+M%22">Nsubuga M</searchLink>; Joint Adherent Brothers and Sisters Against AIDS, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Ajibola+G%22">Ajibola G</searchLink>; Botswana Harvard Health Partnership, Gaborone, Botswana.<br /><searchLink fieldCode="AU" term="%22Bar+KJ%22">Bar KJ</searchLink>; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bengu+N%22">Bengu N</searchLink>; Umkhuseli Innovation and Research Management, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Bwakura-Dangarembizi+M%22">Bwakura-Dangarembizi M</searchLink>; Department of Paediatrics and Child Health, University of Zimbabwe, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Caskey+M%22">Caskey M</searchLink>; Laboratory of Molecular Immunology, Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cromhout+G%22">Cromhout G</searchLink>; Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Kekitiinwa+AR%22">Kekitiinwa AR</searchLink>; Baylor College of Medicine Children's Foundation, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kilembe+W%22">Kilembe W</searchLink>; Center for Family Health Research, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Kuhn+L%22">Kuhn L</searchLink>; Gertrude H Sergievsky Center, Vagelos College of Physicians and Surgeons and Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Likhitwonnawut+U%22">Likhitwonnawut U</searchLink>; Thailand National CAB, Chiang Mai, Thailand.<br /><searchLink fieldCode="AU" term="%22Mgodi+NM%22">Mgodi NM</searchLink>; University of Zimbabwe Clinical Trials Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Persaud+D%22">Persaud D</searchLink>; Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Peluso+MJ%22">Peluso MJ</searchLink>; Division of HIV, Infectious Diseases & Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rasmussen+TA%22">Rasmussen TA</searchLink>; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Romo+M%22">Romo M</searchLink>; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sacdalan+C%22">Sacdalan C</searchLink>; SEARCH Research Foundation, Bangkok, Thailand; Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Samaneka+W%22">Samaneka W</searchLink>; University of Zimbabwe Clinical Trials Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Shapiro+R%22">Shapiro R</searchLink>; Department of Immunology and Infectious Diseases, Harvard T H Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Søgaard+OS%22">Søgaard OS</searchLink>; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Tudor-Williams+G%22">Tudor-Williams G</searchLink>; Department of Infectious Diseases and Centre for Paediatrics and Child Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wambui+C%22">Wambui C</searchLink>; Moi University Clinical Research Centre, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Tressler+R%22">Tressler R</searchLink>; Division of AIDS, National Institute of Allergy and Infectious Diseases; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lewin+SR%22">Lewin SR</searchLink>; Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Crowell+TA%22">Crowell TA</searchLink>; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kasprowicz+VO%22">Kasprowicz VO</searchLink>; Africa Health Research Institute, Durban, South Africa; Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, USA; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Trautmann+L%22">Trautmann L</searchLink>; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: ltrautmann@Global-ID.org.
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