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Dynamic FIB-4 trajectory and a multi-state Markov model analysis reveal fibrosis progression and cardiovascular-cerebrovascular risk in MAFLD patients.

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Title: Dynamic FIB-4 trajectory and a multi-state Markov model analysis reveal fibrosis progression and cardiovascular-cerebrovascular risk in MAFLD patients.
Authors: Fu XY; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Dalian Medical University, Dalian, China., Yan SY; Affiliated Hospital of Jiaxing University(The First Hospital of Jiaxing), Jiaxing, Zhejiang, China., Song YQ; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China., Ye YF; Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China., Ma JL; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China., Yan LL; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China., Liang JW; Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China., Xu SJ; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China., Xu SW; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China., Chen YH; Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: chenyh@enzemed.com., Mao XL; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Institute of Digestive Disease, Taizhou Hospital of Zhejiang Province Affiliated with Wenzhou Medical University, Linhai, Zhejiang, China; Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: maoxl@enzemed.com., Li SW; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Institute of Digestive Disease, Taizhou Hospital of Zhejiang Province Affiliated with Wenzhou Medical University, Linhai, Zhejiang, China; Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: li_shaowei81@hotmail.com.
Source: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2026 Jun; Vol. 36 (6), pp. 104617. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Dynamic FIB-4 trajectory and a multi-state Markov model analysis reveal fibrosis progression and cardiovascular-cerebrovascular risk in MAFLD patients.
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  Data: <searchLink fieldCode="AU" term="%22Fu+XY%22">Fu XY</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Dalian Medical University, Dalian, China.<br /><searchLink fieldCode="AU" term="%22Yan+SY%22">Yan SY</searchLink>; Affiliated Hospital of Jiaxing University(The First Hospital of Jiaxing), Jiaxing, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Song+YQ%22">Song YQ</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Ye+YF%22">Ye YF</searchLink>; Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Ma+JL%22">Ma JL</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Yan+LL%22">Yan LL</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Liang+JW%22">Liang JW</searchLink>; Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xu+SJ%22">Xu SJ</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xu+SW%22">Xu SW</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: chenyh@enzemed.com.<br /><searchLink fieldCode="AU" term="%22Mao+XL%22">Mao XL</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Institute of Digestive Disease, Taizhou Hospital of Zhejiang Province Affiliated with Wenzhou Medical University, Linhai, Zhejiang, China; Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: maoxl@enzemed.com.<br /><searchLink fieldCode="AU" term="%22Li+SW%22">Li SW</searchLink>; Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China; Institute of Digestive Disease, Taizhou Hospital of Zhejiang Province Affiliated with Wenzhou Medical University, Linhai, Zhejiang, China; Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China. Electronic address: li_shaowei81@hotmail.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9111474 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1590-3729 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209394753%22">09394753 </searchLink><i>NLM ISO Abbreviation: </i>Nutr Metab Cardiovasc Dis <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.numecd.2026.104617
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      – Code: eng
        Text: English
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        StartPage: 104617
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      – TitleFull: Dynamic FIB-4 trajectory and a multi-state Markov model analysis reveal fibrosis progression and cardiovascular-cerebrovascular risk in MAFLD patients.
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            NameFull: Fu XY
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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              Value: 36
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            – TitleFull: Nutrition, metabolism, and cardiovascular diseases : NMCD
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