Safety and effectiveness of post-trastuzumab deruxtecan regimens in patients with HER2-positive metastatic breast cancer who discontinued trastuzumab deruxtecan due to interstitial lung disease.
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| Title: | Safety and effectiveness of post-trastuzumab deruxtecan regimens in patients with HER2-positive metastatic breast cancer who discontinued trastuzumab deruxtecan due to interstitial lung disease. |
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| Authors: | Tsurutani J; Advanced Cancer Translational Research Institute, Showa Medical University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. Electronic address: tsurutaj@med.showa-u.ac.jp., Nozawa K; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan., Mukohara T; Department of Medical Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan., Taira T; Department of Oncology, Sagara Hospital, 3-31 Matsubaracho, Kagoshima, Kagoshima, 892-0833, Japan., Yoshimura A; Department of Breast Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 454-8681, Japan., Nagai SE; Division of Breast Oncology, Saitama Cancer Center, 780 Komuro, Inamachi, Kita-Adachi-gun, Saitama, 362-0806, Japan., Hashimoto J; Division of Medical Oncology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan., Matsuura K; Department of Breast Oncology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan., Mizuno T; Department of Medical Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Shinden Y; Department of Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, Kagoshima, 890-8544, Japan., Yamamoto M; Department of Breast Oncology, Hokkaido Cancer Center, 2-3-54 Kikusui shi-jo, Shiroishi-ku, Sapporo, Hokkaido, 003-0804, Japan., Takano T; Department of Breast Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan., Wakahara M; Department of Breast and Endocrine Surgery, Tottori University Hospital, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan., Terakawa H; Department of Breast Surgery, Kanazawa University Hospital, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan., Yamanaka T; Department of Breast Surgery and Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa, 241-8515, Japan., Kojima Y; Institute for Clinical Genetics and Genomics, Showa Medical University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan., Nakayama T; Department of Breast and Endocrine Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, Osaka, 541-8567, Japan., Hirakawa Y; Oncology Medical Science Department I, Daiichi Sankyo Co., Ltd., 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, 103-8426, Japan., Shiosakai K; Data Intelligence Department, Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan., Iwata H; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan. |
| Source: | Breast (Edinburgh, Scotland) [Breast] 2026 Apr; Vol. 86, pp. 104722. Date of Electronic Publication: 2026 Feb 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9213011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3080 (Electronic) Linking ISSN: 09609776 NLM ISO Abbreviation: Breast Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41762808 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety and effectiveness of post-trastuzumab deruxtecan regimens in patients with HER2-positive metastatic breast cancer who discontinued trastuzumab deruxtecan due to interstitial lung disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tsurutani+J%22">Tsurutani J</searchLink>; Advanced Cancer Translational Research Institute, Showa Medical University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan. Electronic address: tsurutaj@med.showa-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Nozawa+K%22">Nozawa K</searchLink>; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Mukohara+T%22">Mukohara T</searchLink>; Department of Medical Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Taira+T%22">Taira T</searchLink>; Department of Oncology, Sagara Hospital, 3-31 Matsubaracho, Kagoshima, Kagoshima, 892-0833, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshimura+A%22">Yoshimura A</searchLink>; Department of Breast Oncology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 454-8681, Japan.<br /><searchLink fieldCode="AU" term="%22Nagai+SE%22">Nagai SE</searchLink>; Division of Breast Oncology, Saitama Cancer Center, 780 Komuro, Inamachi, Kita-Adachi-gun, Saitama, 362-0806, Japan.<br /><searchLink fieldCode="AU" term="%22Hashimoto+J%22">Hashimoto J</searchLink>; Division of Medical Oncology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8560, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuura+K%22">Matsuura K</searchLink>; Department of Breast Oncology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.<br /><searchLink fieldCode="AU" term="%22Mizuno+T%22">Mizuno T</searchLink>; Department of Medical Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Shinden+Y%22">Shinden Y</searchLink>; Department of Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, Kagoshima, 890-8544, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; Department of Breast Oncology, Hokkaido Cancer Center, 2-3-54 Kikusui shi-jo, Shiroishi-ku, Sapporo, Hokkaido, 003-0804, Japan.<br /><searchLink fieldCode="AU" term="%22Takano+T%22">Takano T</searchLink>; Department of Breast Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Wakahara+M%22">Wakahara M</searchLink>; Department of Breast and Endocrine Surgery, Tottori University Hospital, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan.<br /><searchLink fieldCode="AU" term="%22Terakawa+H%22">Terakawa H</searchLink>; Department of Breast Surgery, Kanazawa University Hospital, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.<br /><searchLink fieldCode="AU" term="%22Yamanaka+T%22">Yamanaka T</searchLink>; Department of Breast Surgery and Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa, 241-8515, Japan.<br /><searchLink fieldCode="AU" term="%22Kojima+Y%22">Kojima Y</searchLink>; Institute for Clinical Genetics and Genomics, Showa Medical University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Nakayama+T%22">Nakayama T</searchLink>; Department of Breast and Endocrine Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Hirakawa+Y%22">Hirakawa Y</searchLink>; Oncology Medical Science Department I, Daiichi Sankyo Co., Ltd., 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, 103-8426, Japan.<br /><searchLink fieldCode="AU" term="%22Shiosakai+K%22">Shiosakai K</searchLink>; Data Intelligence Department, Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan.<br /><searchLink fieldCode="AU" term="%22Iwata+H%22">Iwata H</searchLink>; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229213011%22">Breast (Edinburgh, Scotland)</searchLink> [Breast] 2026 Apr; Vol. 86, pp. 104722. <i>Date of Electronic Publication: </i>2026 Feb 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9213011 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-3080 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209609776%22">09609776 </searchLink><i>NLM ISO Abbreviation: </i>Breast <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41762808 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.breast.2026.104722 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 104722 Titles: – TitleFull: Safety and effectiveness of post-trastuzumab deruxtecan regimens in patients with HER2-positive metastatic breast cancer who discontinued trastuzumab deruxtecan due to interstitial lung disease. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tsurutani J – PersonEntity: Name: NameFull: Nozawa K – PersonEntity: Name: NameFull: Mukohara T – PersonEntity: Name: NameFull: Taira T – PersonEntity: Name: NameFull: Yoshimura A – PersonEntity: Name: NameFull: Nagai SE – PersonEntity: Name: NameFull: Hashimoto J – PersonEntity: Name: NameFull: Matsuura K – PersonEntity: Name: NameFull: Mizuno T – PersonEntity: Name: NameFull: Shinden Y – PersonEntity: Name: NameFull: Yamamoto M – PersonEntity: Name: NameFull: Takano T – PersonEntity: Name: NameFull: Wakahara M – PersonEntity: Name: NameFull: Terakawa H – PersonEntity: Name: NameFull: Yamanaka T – PersonEntity: Name: NameFull: Kojima Y – PersonEntity: Name: NameFull: Nakayama T – PersonEntity: Name: NameFull: Hirakawa Y – PersonEntity: Name: NameFull: Shiosakai K – PersonEntity: Name: NameFull: Iwata H IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-3080 Numbering: – Type: volume Value: 86 Titles: – TitleFull: Breast (Edinburgh, Scotland) Type: main |
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