Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma.

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Title: Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma.
Authors: Karnan S; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. skarnan@aichi-med-u.ac.jp., Ota A; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. aota@kinjo-u.ac.jp.; Department of Food and Nutritional Environment, College of Human Life and Environment, Kinjo Gakuin University, Nagoya, Aichi, Japan. aota@kinjo-u.ac.jp., Hasan MN; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Murakami H; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Rahman ML; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Wahiduzzaman M; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Foundations of Medicine, NYU Grossman Long Island School of Medicine, Mineola, NY, USA., Shihan MTA; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh., Jahan N; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh., Vu LQ; Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Hanamura I; Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Inoko A; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Riku M; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Ito H; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Kaneko Y; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Lin Y; Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Japan.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Hyodo T; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Konishi H; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Tsuzuki S; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan., Hosokawa Y; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 28; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma.
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  Data: <searchLink fieldCode="AU" term="%22Karnan+S%22">Karnan S</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. skarnan@aichi-med-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ota+A%22">Ota A</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. aota@kinjo-u.ac.jp.; Department of Food and Nutritional Environment, College of Human Life and Environment, Kinjo Gakuin University, Nagoya, Aichi, Japan. aota@kinjo-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Hasan+MN%22">Hasan MN</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Murakami+H%22">Murakami H</searchLink>; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Rahman+ML%22">Rahman ML</searchLink>; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Wahiduzzaman+M%22">Wahiduzzaman M</searchLink>; EuGEF Research Foundation, Chattogram, Bangladesh.; Department of Foundations of Medicine, NYU Grossman Long Island School of Medicine, Mineola, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shihan+MTA%22">Shihan MTA</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Jahan+N%22">Jahan N</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.; EuGEF Research Foundation, Chattogram, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Vu+LQ%22">Vu LQ</searchLink>; Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Hanamura+I%22">Hanamura I</searchLink>; Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Inoko+A%22">Inoko A</searchLink>; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Riku+M%22">Riku M</searchLink>; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+H%22">Ito H</searchLink>; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneko+Y%22">Kaneko Y</searchLink>; Department of Pathology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Japan.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Hyodo+T%22">Hyodo T</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Konishi+H%22">Konishi H</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuzuki+S%22">Tsuzuki S</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Hosokawa+Y%22">Hosokawa Y</searchLink>; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Feb 28; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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