Bioorthogonal catalytic centres engineered for gastrointestinal stabilization provide oral delivery for the treatment of gastric cancer.

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Title: Bioorthogonal catalytic centres engineered for gastrointestinal stabilization provide oral delivery for the treatment of gastric cancer.
Authors: Shanmugam MK; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore, 117600, Singapore., Vallerinteavide Mavelli G; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Yuze P; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Damle HS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Pakkiri LS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Wu LH; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.; Department of Pharmacy, Faculty of Science, 18 Science Drive 4, National University of Singapore, Singapore, 117559, Singapore., Leong LP; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Vaidya SS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Sadeghi S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore., Sethi G; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore, 117600, Singapore., Drum CL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore. mdccld@nus.edu.sg.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Feb 28; Vol. 24 (1). Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
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  Data: Bioorthogonal catalytic centres engineered for gastrointestinal stabilization provide oral delivery for the treatment of gastric cancer.
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  Data: <searchLink fieldCode="AU" term="%22Shanmugam+MK%22">Shanmugam MK</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore, 117600, Singapore.<br /><searchLink fieldCode="AU" term="%22Vallerinteavide+Mavelli+G%22">Vallerinteavide Mavelli G</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Yuze+P%22">Yuze P</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Damle+HS%22">Damle HS</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Pakkiri+LS%22">Pakkiri LS</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Wu+LH%22">Wu LH</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.; Department of Pharmacy, Faculty of Science, 18 Science Drive 4, National University of Singapore, Singapore, 117559, Singapore.<br /><searchLink fieldCode="AU" term="%22Leong+LP%22">Leong LP</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Vaidya+SS%22">Vaidya SS</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Sadeghi+S%22">Sadeghi S</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Sethi+G%22">Sethi G</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 16 Medical Drive, Singapore, 117600, Singapore.<br /><searchLink fieldCode="AU" term="%22Drum+CL%22">Drum CL</searchLink>; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 119228, Singapore. mdccld@nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2026 Feb 28; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Feb 28.
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        Value: 10.1186/s12951-026-04065-2
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        Text: English
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            – D: 28
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              Text: 2026 Feb 28
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