Hormone therapy use and duration with postoperative radiotherapy for recurrent prostate cancer: an individual patient data meta-analysis.

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Title: Hormone therapy use and duration with postoperative radiotherapy for recurrent prostate cancer: an individual patient data meta-analysis.
Authors: Kishan AU; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: aukishan@mednet.ucla.edu., Sun Y; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Parker CC; The Royal Marsden NHS Foundation Trust, London, UK; The Institute of Cancer Research, London, UK., Sargos P; Institut Bergonié, Bordeaux, France., Sydes MR; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Chabaud S; Clinical Research Department, Centre Léon Bérard, Lyon, France., Brihoum M; Unicancer, Paris, France., Kalbasi TR; Department of Medicine Statistical Core, University of California, Los Angeles, Los Angeles, CA, USA., Steinberg ML; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA., Valle LF; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA., Taparra K; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA; School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA., Shoag JE; Department of Urology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Garcia JA; Department of Medicine, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Brown JR; Department of Medicine, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Rettig MB; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Singer AE; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Reiter RE; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA., Eggener S; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA., Brisbane W; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA., Roy S; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Zaorsky NG; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Jia AY; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Ma TM; Department of Radiation Oncology, University of Washington, Seattle, WA, USA., Nickols NG; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA; Department of Radiation Oncology, Greater Los Angeles VA, Los Angeles, CA, USA., Efstathiou JA; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Mohamad O; Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA; Department of American University of Beirut, Beirut, Lebanon., Dignam JJ; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA; NRG Oncology Statistics and Data Management Center, Philadelphia, PA., Seiferheld WF; NRG Oncology Statistics and Data Management Center, Philadelphia, PA., Pollack A; Department of Radiation Oncology, Miller School of Medicine and Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA., Sandler HM; Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Nguyen PL; Department of Radiation Oncology, Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA., Pommier P; Clinical Research Department, Centre Léon Bérard, Lyon, France; Department of Radiotherapy, Institut Curie, Paris, France., Spratt DE; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Source: Lancet (London, England) [Lancet] 2026 Mar 14; Vol. 407 (10533), pp. 1059-1071. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
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  Data: Hormone therapy use and duration with postoperative radiotherapy for recurrent prostate cancer: an individual patient data meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Kishan+AU%22">Kishan AU</searchLink>; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: aukishan@mednet.ucla.edu.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Parker+CC%22">Parker CC</searchLink>; The Royal Marsden NHS Foundation Trust, London, UK; The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Sargos+P%22">Sargos P</searchLink>; Institut Bergonié, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Sydes+MR%22">Sydes MR</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chabaud+S%22">Chabaud S</searchLink>; Clinical Research Department, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Brihoum+M%22">Brihoum M</searchLink>; Unicancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kalbasi+TR%22">Kalbasi TR</searchLink>; Department of Medicine Statistical Core, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Steinberg+ML%22">Steinberg ML</searchLink>; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Valle+LF%22">Valle LF</searchLink>; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Taparra+K%22">Taparra K</searchLink>; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA; School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shoag+JE%22">Shoag JE</searchLink>; Department of Urology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+JA%22">Garcia JA</searchLink>; Department of Medicine, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Department of Medicine, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Rettig+MB%22">Rettig MB</searchLink>; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Singer+AE%22">Singer AE</searchLink>; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reiter+RE%22">Reiter RE</searchLink>; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eggener+S%22">Eggener S</searchLink>; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brisbane+W%22">Brisbane W</searchLink>; Department of Urology, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Roy+S%22">Roy S</searchLink>; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Zaorsky+NG%22">Zaorsky NG</searchLink>; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Jia+AY%22">Jia AY</searchLink>; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Ma+TM%22">Ma TM</searchLink>; Department of Radiation Oncology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Nickols+NG%22">Nickols NG</searchLink>; Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, USA; Department of Radiation Oncology, Greater Los Angeles VA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Efstathiou+JA%22">Efstathiou JA</searchLink>; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mohamad+O%22">Mohamad O</searchLink>; Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA; Department of American University of Beirut, Beirut, Lebanon.<br /><searchLink fieldCode="AU" term="%22Dignam+JJ%22">Dignam JJ</searchLink>; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA; NRG Oncology Statistics and Data Management Center, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Seiferheld+WF%22">Seiferheld WF</searchLink>; NRG Oncology Statistics and Data Management Center, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pollack+A%22">Pollack A</searchLink>; Department of Radiation Oncology, Miller School of Medicine and Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sandler+HM%22">Sandler HM</searchLink>; Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+PL%22">Nguyen PL</searchLink>; Department of Radiation Oncology, Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pommier+P%22">Pommier P</searchLink>; Clinical Research Department, Centre Léon Bérard, Lyon, France; Department of Radiotherapy, Institut Curie, Paris, France.<br /><searchLink fieldCode="AU" term="%22Spratt+DE%22">Spratt DE</searchLink>; Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
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